3.1.22.1: deoxyribonuclease II

This is an abbreviated version, for detailed information about deoxyribonuclease II, go to the full flat file.

Reaction

endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products =

Synonyms

acid deoxyribonuclease, acid DNase, deoxyribonuclease II, deoxyribonuclease IIalpha, deoxyribonuclease IIbeta, deoxyribonucleate 3'-nucleotidohydrolase, DNase 2, DNase 2a, DNase II, DNase II homolog, DNase IIalpha, DNase IIb, DNase IIbeta, EC 3.1.4.6, L-DNase II, LEI, LEI-derived DNase II, LEI/L-DNase II, leukocyte elastase inhibitor-derived DNase II, leukocyte elastase inhibitor/LEI-derived DNase II, lysosomal DNase II, Nuc-1, NUC-1 apoptotic nuclease, pancreatic DNase II, plancitoxin 1, R31240_2

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters
                3.1.22.1 deoxyribonuclease II

Specific Activity

Specific Activity on EC 3.1.22.1 - deoxyribonuclease II

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.002
-
-
0.42 - 0.51
-
-
4.4
-
1fold purified
138
-
mutant H207L, pH 4.7
172
-
mutant H274L, pH 4.7
219
-
mutant H206L, pH 4.7
220
-
mutant H41L, pH 4.7
287
-
mutant H109L, pH 4.7
321
-
wild-type, pH 4.7
327.1
-
74.3fold purified
331
-
mutant H322L, pH 4.7
302000
-
pH 5.0
additional information