3.1.22.1: deoxyribonuclease II

This is an abbreviated version, for detailed information about deoxyribonuclease II, go to the full flat file.

Reaction

endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products =

Synonyms

acid deoxyribonuclease, acid DNase, deoxyribonuclease II, deoxyribonuclease IIalpha, deoxyribonuclease IIbeta, deoxyribonucleate 3'-nucleotidohydrolase, DNase 2, DNase 2a, DNase II, DNase II homolog, DNase IIalpha, DNase IIb, DNase IIbeta, EC 3.1.4.6, L-DNase II, LEI, LEI-derived DNase II, LEI/L-DNase II, leukocyte elastase inhibitor-derived DNase II, leukocyte elastase inhibitor/LEI-derived DNase II, lysosomal DNase II, Nuc-1, NUC-1 apoptotic nuclease, pancreatic DNase II, plancitoxin 1, R31240_2

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters
                3.1.22.1 deoxyribonuclease II

Metals Ions

Metals Ions on EC 3.1.22.1 - deoxyribonuclease II

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
-
more than 50% activation at 10 mM
Co2+
-
slight activation at 10 mM, inhibition at higher concentrations
CuCl2
-
high concentrations cause cyclic changes in the enzyme activity, the changes of enzyme activity are likely to be caused by adaption and compensation processes in the organisms of the molluscs exposed to toxicants in vivo
CuSO4
-
high concentrations cause cyclic changes in the enzyme activity, the changes of enzyme activity are likely to be caused by adaption and compensation processes in the organisms of the molluscs exposed to toxicants in vivo
Mn2+
-
slight activation at 10 mM, inhibition at higher concentrations
additional information