3.1.21.7: deoxyribonuclease V

This is an abbreviated version!
For detailed information about deoxyribonuclease V, go to the full flat file.

Word Map on EC 3.1.21.7

3.1.21.7

nick

deaminate

phosphodiester

beta-polymerase

deoxyinosine-containing

3\'-hydroxyl

proofreading

biotechnology

analysis

molecular biology

drug development

medicine

Reaction

endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate =

Synonyms

AGTendoV, deoxyinosine 3' endonuclease, Deoxyinosine 3'endonuclease, DNase V, EC 3.1.22.3, endo V, endodeoxyribonuclease V, endonuclease V, EndoV, Escherichia coli endodeoxyribonuclease V, nfi, PF0987, PfuEndoV, T4 endonuclease V, T4 UV endonuclease, Tb10.6k15.3890

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters

3.1.21.7 deoxyribonuclease V

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Results	in table
4	Activating Compound
8025	AA Sequence
5	Application
1	CAS Registry Number
19	Cloned(Commentary)
8	Crystallization (Commentary)
4	Disease/ Diagnostics
20	General Information
1	General Stability
18	Inhibitors
4	KM Value [mM]
13	Localization
27	Metals/Ions
13	Molecular Weight [Da]
38	Natural Substrates/ Products (Substrates)
63	Organism
18	PDB ID
13	pH Optimum
3	pH Range
2	pH Stability
1	pI Value
99	Protein Variants
29	Purification (Commentary)
1	Reaction
2	Reaction Type
63	Reference
19	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
100	Substrates and Products (Substrate)
9	Subunits
70	Synonyms
7	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 3.1.21.7 - deoxyribonuclease V

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10000

Tequatrovirus T4

2 * 10000, SDS-PAGE, in the presence of 100 mM KCl

13000

4 * 13000, SDS-PAGE

16000

19000

Tequatrovirus T4

gel filtration in the presence of 100 mM KCl

288780

20000

Escherichia coli

glycerol density gradient sedimentation

288786

23580

Pyrococcus furiosus

Q8U263

x * 23580, calculated from sequence, His-tagged enzyme

731387

27000

Escherichia coli

glycerol density gradient centrifugation

288788

27800

Homo sapiens

Q8N8Q3

1 * 27800, calculated from amino acid sequence

28800

1 * 28800, SDS-PAGE

34922

Trypanosoma brucei brucei

Q38AS1

calculated from sequence

752230

53000

Bos taurus

sucrose density gradient centrifugation

55000

SDS-PAGE