3.1.21.7: deoxyribonuclease V

This is an abbreviated version!
For detailed information about deoxyribonuclease V, go to the full flat file.

Reaction

endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate =

Synonyms

AGTendoV, deoxyinosine 3' endonuclease, Deoxyinosine 3'endonuclease, DNase V, EC 3.1.22.3, endo V, endodeoxyribonuclease V, endonuclease V, EndoV, Escherichia coli endodeoxyribonuclease V, nfi, PF0987, PfuEndoV, T4 endonuclease V, T4 UV endonuclease, Tb10.6k15.3890

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters

                3.1.21.7 deoxyribonuclease V

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Results	in table
4	Activating Compound
8025	AA Sequence
5	Application
1	CAS Registry Number
19	Cloned(Commentary)
8	Crystallization (Commentary)
4	Disease/ Diagnostics
20	General Information
1	General Stability
18	Inhibitors
4	KM Value [mM]
13	Localization
27	Metals/Ions
13	Molecular Weight [Da]
38	Natural Substrates/ Products (Substrates)
63	Organism
18	PDB ID
13	pH Optimum
3	pH Range
2	pH Stability
1	pI Value
99	Protein Variants
29	Purification (Commentary)
1	Reaction
2	Reaction Type
63	Reference
19	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
100	Substrates and Products (Substrate)
9	Subunits
70	Synonyms
7	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

Disease

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Disease on EC 3.1.21.7 - deoxyribonuclease V

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Liver Neoplasms, Experimental

Interaction of mammalian deoxyribonuclease V, a double strand 3' to 5' and 5' to 3' exonuclease, with deoxyribonucleic acid polymerase-beta from the Novikoff hepatoma.

6253467

Neoplasms

Switching base preferences of mismatch cleavage in endonuclease V: an improved method for scanning point mutations.

17130153

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