3.1.21.7: deoxyribonuclease V

This is an abbreviated version!
For detailed information about deoxyribonuclease V, go to the full flat file.

Word Map on EC 3.1.21.7

3.1.21.7

nick

deaminate

phosphodiester

beta-polymerase

deoxyinosine-containing

3\'-hydroxyl

proofreading

biotechnology

analysis

molecular biology

drug development

medicine

Reaction

endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate =

Synonyms

AGTendoV, deoxyinosine 3' endonuclease, Deoxyinosine 3'endonuclease, DNase V, EC 3.1.22.3, endo V, endodeoxyribonuclease V, endonuclease V, EndoV, Escherichia coli endodeoxyribonuclease V, nfi, PF0987, PfuEndoV, T4 endonuclease V, T4 UV endonuclease, Tb10.6k15.3890

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters

3.1.21.7 deoxyribonuclease V

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Results	in table
4	Activating Compound
8025	AA Sequence
5	Application
1	CAS Registry Number
19	Cloned(Commentary)
8	Crystallization (Commentary)
4	Disease/ Diagnostics
20	General Information
1	General Stability
18	Inhibitors
4	KM Value [mM]
13	Localization
27	Metals/Ions
13	Molecular Weight [Da]
38	Natural Substrates/ Products (Substrates)
63	Organism
18	PDB ID
13	pH Optimum
3	pH Range
2	pH Stability
1	pI Value
99	Protein Variants
29	Purification (Commentary)
1	Reaction
2	Reaction Type
63	Reference
19	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
100	Substrates and Products (Substrate)
9	Subunits
70	Synonyms
7	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 3.1.21.7 - deoxyribonuclease V

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6.6

7 - 7.5

activity for deoxyinosine-containing DNA

288775

7.5 - 9

Thermococcus barophilus

A0A0S1X9V3

750798

7.6

Escherichia coli

endonuclease V incision assay

714813

7.9

Escherichia coli

reconstituted endonuclease V-mediated excision repair assay at

714813

Escherichia coli

mismatch repair activity

288775

8 - 8.5

Escherichia coli

activity for deoxyuridine-containing DNA

8.5

9.2

9.5