1.1.1.56: ribitol 2-dehydrogenase
This is an abbreviated version!
For detailed information about ribitol 2-dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.56
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1.1.1.56
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klebsiella
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aerogenes
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xylitol
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polyols
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pentitols
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d-arabitol
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d-fructose
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superproduce
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d-sorbitol
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erythritol
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zymomonas
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d-mannitol
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d-ribulose
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d-ribulokinase
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phlei
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l-xylulose
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d-glucitol
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synthesis
- 1.1.1.56
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klebsiella
- aerogenes
- xylitol
- polyols
- pentitols
- d-arabitol
- d-fructose
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superproduce
- d-sorbitol
- erythritol
-
zymomonas
- d-mannitol
- d-ribulose
- d-ribulokinase
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phlei
- l-xylulose
- d-glucitol
- synthesis
Reaction
Synonyms
adonitol dehydrogenase, NAD+-dependent ribitol dehydrogenase, RDH, ribitol dehydrogenase, ribitol dehydrogenase A, ribitol dehydrogenase B, ribitol dehydrogenase D, ribitol-specific dehydrogenase, ribitol: NAD+ 2-oxidoreductase, SpRDH
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.56 - ribitol 2-dehydrogenase
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REACTION DIAGRAM
D-ribitol + NAD+
D-ribulose + NADH + H+
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the catalytic amino acid residues of SpRDH consist of Cys37, His65, Glu66, and Glu157
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ribitol + NAD+
D-ribulose + NADH
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ribitol + NAD+
D-ribulose + NADH + H+
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high activity
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xylitol + NAD+
D-xylulose + NADH + H+
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mutants have increased xylitol activity
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additional information
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no activity with NADP+
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additional information
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the enzyme shows 8.6% activity with allitol, low activity with xylitol (1.8%) and no activity with D-sorbitol, L-arabitol, galactitol, D-mannitol, inositol and glycerol
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additional information
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the enzyme shows 8.6% activity with allitol, low activity with xylitol (1.8%) and no activity with D-sorbitol, L-arabitol, galactitol, D-mannitol, inositol and glycerol
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additional information
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no dehydrogenation activity for D-mannitol, D-sorbitol, D-galactitol, myo-inositol, or glycerol
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