1.1.1.56: ribitol 2-dehydrogenase

This is an abbreviated version, for detailed information about ribitol 2-dehydrogenase, go to the full flat file.

Reaction

ribitol
+
NAD+
=
D-ribulose
+
NADH
+
H+

Synonyms

adonitol dehydrogenase, NAD+-dependent ribitol dehydrogenase, RDH, ribitol dehydrogenase A, ribitol dehydrogenase B, ribitol dehydrogenase D, ribitol-specific dehydrogenase, ribitol: NAD+ 2-oxidoreductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.56 ribitol 2-dehydrogenase

Temperature Stability

Temperature Stability on EC 1.1.1.56 - ribitol 2-dehydrogenase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 60
-
50% enzyme activity loss after 1 min to 15 days
25 - 50
-
the enzyme retains 72, 72, 48 and 0% of its initial activity after 4 h at 25, 30, 40 and 50°C, respectively
37
-
extensive activity loss at pH 8 for 15 min
40 - 60
the enzyme shows half-lives of 25.7, 15.3, 7.5, 3.1, and 0.45 h at 40°C, 45°C, 50°C, 55°C, and 60°C, respectively
55
-
half-life of mutant B is 6 min, half-life of mutant D is 30 min, half-life of wild-type enzyme is 20 min