1.1.1.56: ribitol 2-dehydrogenase

This is an abbreviated version, for detailed information about ribitol 2-dehydrogenase, go to the full flat file.

Reaction

ribitol
+
NAD+
=
D-ribulose
+
NADH
+
H+

Synonyms

adonitol dehydrogenase, NAD+-dependent ribitol dehydrogenase, RDH, ribitol dehydrogenase A, ribitol dehydrogenase B, ribitol dehydrogenase D, ribitol-specific dehydrogenase, ribitol: NAD+ 2-oxidoreductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.56 ribitol 2-dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.56 - ribitol 2-dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
competitive to ribitol
Ag+
-
complete inhibition
Chelating agents
-
-
diethyldithiocarbamate
-
50% inhibition at a concentration of 50 mM
dithiothreitol
-
-
EDTA
the enzyme activity is mostly lost (about 97%) after EDTA treatment
Fe3+
27.2% residual activity at 5 mM
K+
73.6% residual activity at 5 mM
Ni2+
-
10-20% inhibition
o-phenanthroline
-
50% inhibition at a concentration of 50 mM
p-chloromercuribenzoate
-
-
p-mercuribenzoate
-
reversible by L-cysteine