1.1.1.34: hydroxymethylglutaryl-CoA reductase (NADPH)

This is an abbreviated version, for detailed information about hydroxymethylglutaryl-CoA reductase (NADPH), go to the full flat file.

Reaction

(R)-mevalonate
+
CoA
+ 2 NADP+ =
(S)-3-hydroxy-3-methylglutaryl-CoA
+ 2 NADPH + 2 H+

Synonyms

3-hydroxy-3-methyl-glutaryl CoA reductase, 3-hydroxy-3-methylglutaryl Ccoenzyme A reductase 1, 3-hydroxy-3-methylglutaryl co-enzyme A reductase, 3-hydroxy-3-methylglutaryl CoA reductase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, 3-hydroxy-3-methylglutaryl coenzyme A reductase 1, 3-hydroxy-3-methylglutaryl-CoA reductase, 3-hydroxy-3-methylglutaryl-CoA reductase (NADPH), 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-hydroxymethylglutaryl coenzyme A reductase, acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, beta-hydroxy-beta-methylglutaryl coenzyme A reductase, beta-hydroxy-beta-methylglutaryl-Co A reductase, EuHMGR, HMG CoA reductase, HMG-CoA reductase, HMG-CoAR, HMG1, HMG2, HMG2.2, Hmg2p, HMG3.3, HMGCoA reductase, HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating CoA), HMGCoAR, HMGCR, HMGR, HMGR1, HMGR1S, HMGR2, hydroxy-3-methylglutoryl-Coenzyme A reductase, hydroxymethylglutaryl CoA reductase (NADPH), hydroxymethylglutaryl-coenzyme A reductase (reduced nicotinamide adenine dinucleotide phosphate), mevalonate:NADP+ oxidoreductase (acetylating CoA), microsomal HMG-CoA reductase, NADPH-hydroxymethylglutaryl-CoA reductase, S-3-hydroxy-3-methylglutaryl-CoA reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)

Synonyms

Synonyms on EC 1.1.1.34 - hydroxymethylglutaryl-CoA reductase (NADPH)

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SYNONYMS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3-hydroxy-3-methyl-glutaryl CoA reductase
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3-hydroxy-3-methylglutaryl Ccoenzyme A reductase 1
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3-hydroxy-3-methylglutaryl co-enzyme A reductase
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3-hydroxy-3-methylglutaryl CoA reductase
3-hydroxy-3-methylglutaryl coenzyme A reductase
3-hydroxy-3-methylglutaryl coenzyme A reductase 1
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3-hydroxy-3-methylglutaryl-CoA reductase
3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)
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3-hydroxy-3-methylglutaryl-coenzyme A reductase
3-hydroxymethylglutaryl coenzyme A reductase
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acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase
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beta-hydroxy-beta-methylglutaryl coenzyme A reductase
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beta-hydroxy-beta-methylglutaryl-Co A reductase
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HMG CoA reductase
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HMG-CoA reductase
HMG-CoAR
HMG2.2
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HMG3.3
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HMGCoA reductase
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HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating CoA)
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HMGCR
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hydroxy-3-methylglutoryl-Coenzyme A reductase
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hydroxymethylglutaryl CoA reductase (NADPH)
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hydroxymethylglutaryl-coenzyme A reductase (reduced nicotinamide adenine dinucleotide phosphate)
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mevalonate:NADP+ oxidoreductase (acetylating CoA)
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microsomal HMG-CoA reductase
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NADPH-hydroxymethylglutaryl-CoA reductase
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S-3-hydroxy-3-methylglutaryl-CoA reductase
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