1.1.1.169: 2-dehydropantoate 2-reductase

This is an abbreviated version, for detailed information about 2-dehydropantoate 2-reductase, go to the full flat file.

Reaction

(R)-pantoate
+
NADP+
=
2-dehydropantoate
+
NADPH
+
H+

Synonyms

2-dehydropantoate 2-reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, 2-oxopantoate reductase, ketopantoate reductase, ketopantoic acid reductase, KPA reductase, KPR, More, panG, Tk-KPR, TK1968 protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.169 2-dehydropantoate 2-reductase

pH Optimum

pH Optimum on EC 1.1.1.169 - 2-dehydropantoate 2-reductase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5
-
reduction of ketopantoic acid with NADPH
5.5
-
reduction of ketopantoic acid with NADH
6
-
reduction of ketopantoic acid
6.3
-
reduction of pantoic acid at 42°C
6.4
recombinant enzyme
7.5
-
assay at
7.6
-
assay at
8.5
-
oxidation of D-pantoic acid
additional information
-
activity decreases with pH increase, reduction of ketopantoic acid