1.1.1.169: 2-dehydropantoate 2-reductase

This is an abbreviated version, for detailed information about 2-dehydropantoate 2-reductase, go to the full flat file.

Reaction

(R)-pantoate
+
NADP+
=
2-dehydropantoate
+
NADPH
+
H+

Synonyms

2-dehydropantoate 2-reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, 2-oxopantoate reductase, ketopantoate reductase, ketopantoic acid reductase, KPA reductase, KPR, More, panG, Tk-KPR, TK1968 protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.169 2-dehydropantoate 2-reductase

Substrates Products

Substrates Products on EC 1.1.1.169 - 2-dehydropantoate 2-reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-pantoate + NAD+
2-dehydropantoate + NADH + H+
show the reaction diagram
(R)-pantoate + NADP+
2-dehydropantoate + NADPH + H+
show the reaction diagram
(S)-pantoate + NAD+
2-dehydropantoate + NADH + H+
show the reaction diagram
low activity
-
-
r
(S)-pantoate + NADP+
2-dehydropantoate + NADPH + H+
show the reaction diagram
low activity
-
-
r
2-dehydropantoate + NADH + H+
(R)-pantoate + NAD+
show the reaction diagram
2-dehydropantoate + NADPH
(R)-pantoate + NADP+
show the reaction diagram
2-dehydropantoate + NADPH + H+
(R)-pantoate + NADP+
show the reaction diagram
-
-
-
r
2-keto-3-hydroxyisovalerate + NADPH
? + NADP+
show the reaction diagram
2-oxoisovalerate + NADPH
2-hydroxyvalerate + NADP+
show the reaction diagram
-
low activity
-
-
r
2-oxopantoate + 3'-NADPH
(R)-pantoate + 3'-NADP+
show the reaction diagram
-
-
-
-
r
2-oxopantoate + alpha-NADPH
(R)-pantoate + alpha-NADP+
show the reaction diagram
-
-
-
-
r
2-oxopantoate + beta-NADPH
(R)-pantoate + beta-NADP+
show the reaction diagram
-
highly specific for
-
-
r
2-oxopantoate + NADPH
(R)-pantoate + NADP+
show the reaction diagram
2-oxopantoate + thio-NADPH
(R)-pantoate + thio-NADP+
show the reaction diagram
-
-
-
-
r
3-methyl-2-oxo-n-valerate + NADPH
2-hydroxy-3-methyl-n-valerate + NADP+
show the reaction diagram
-
low activity
-
-
r
alpha-ketopantoate + NADPH
D-pantoate + NADP+
show the reaction diagram
ketopantoate + ?
pantothenate + ?
show the reaction diagram
-
-
-
?
ketopantoate + NADPH
pantoate + NADP+
show the reaction diagram
ketopantoic acid + ?
D-pantoic acid
show the reaction diagram
ketopantoic acid + NADH
pantoic acid + NAD+
show the reaction diagram
-
-
-
?
ketopantoic acid + NADPH
D-pantoic acid + NADP+
show the reaction diagram
ketopantoic acid + NADPH
pantoic acid + NADP+
show the reaction diagram
additional information
?
-