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Information on EC 3.1.3.74 - pyridoxal phosphatase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.74 pyridoxal phosphatase
IUBMB Comments
Requires Mg2+. This enzyme is specific for phosphorylated vitamin B6 compounds: it acts not only on pyridoxal phosphate (PLP), but also on pyridoxine phosphate (PNP), pyridoxamine phosphate (PMP), 4-pyridoxic acid phosphate and 4-deoxypyridoxine phosphate. This reaction can also be carried out by EC 3.1.3.1 (alkaline phosphatase) and EC 3.1.3.2 (acid phosphatase), but these enzymes have very broad substrate specificities.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
plpp/cin, plp phosphatase, pyridoxal phosphate phosphatase, plpase, pyridoxine phosphate phosphatase, pnp phosphatase, pyridoxal-5'-phosphate phosphatase, pyridoxine 5'-phosphate phosphatase, pyridoxal-specific phosphatase, pyridoxal-5'-phosphate phosphatase/chronophin, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate
show the reaction diagram
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