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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.74physiological function PDXP transgenic mice have immature spines with small heads, while PDXP knockout mice have gigantic spines. PDXP transgenic mice exhibit enhanced synaptic plasticity, while knockout mice show abnormal synaptic plasticity. PDXP also enhances N-methyl-D-aspartate receptor (GluN) functionality by regulating the coupling of GluN2A with interacting proteins, particularly postsynaptic density-95 752194
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.74physiological function pyridoxal-5'-phosphate phosphatase/chronophin, i.e. PLPP/CIN, regulates phosphorylation of ADF/cofilin levels. PLPP/CIN level show a direct proportionality to nuclear translocation of ADF/cofilin. Nuclear accumulation of ADF/cofilin itself may not induce apoptogenic events, but may play a synergic role in apoptosis-like astroglial loss following status epilepticus, detailed analysis, overview -, 715124
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