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EC Number
Metals/Ions
Commentary
Reference
3.1.3.74
CaCl2
enzyme has 17% as much activity with 1 mM CaCl2 than with MgCl2
655965
3.1.3.74
Co2+
highest activity at 5 mM, either Mg2+ or Co2+ required
667526
3.1.3.74
Co2+
most effective to stimulate activity
667526
3.1.3.74
Co2+
similar activation as by Mg2+ and Ni2+, kinetics
654327
3.1.3.74
Cu2+
enzyme has 4% as much activity with 1 mM Cu2+ than with MgCl2
655965
3.1.3.74
Fe2+
-
667526
3.1.3.74
Mg2+
-
667526
3.1.3.74
Mg2+
either Mg2+ or Mn2+ required, highest activity at 2 mM
668013
3.1.3.74
Mg2+
highest activity at 15 mM, either Mg2+ or Co2+ required
667526
3.1.3.74
Mg2+
MgCl2, required for activity, best activator
655965
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