EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.1.3.74 | 4-deoxypyridoxine 5'-phosphate + H2O |
- |
Homo sapiens |
4-deoxypyridoxine + phosphate |
- |
? |
| 3.1.3.74 | 4-pyridoxic acid 5'-phosphate + H2O |
highest catalytic efficiency with 4-pyridoxic acid 5-phosphate and pyridoxal 5-phosphate |
Homo sapiens |
4-pyridoxic acid + phosphate |
- |
? |
| 3.1.3.74 | 4-pyridoxic acid 5'-phosphate + H2O |
the catalytic efficiency decreases in the following order: pyridoxal 5-phosphate, 4-pyridoxic acid 5-phosphate, pyridoxine 5-phosphate and pyridoxamine 5-phosphate |
Homo sapiens |
4-pyridoxic acid + phosphate |
- |
? |
| 3.1.3.74 | more |
probably plays an important role in the regulation of vitamin B6 metabolism |
Homo sapiens |
? |
- |
? |
| 3.1.3.74 | more |
vitamin B6 metabolism |
Homo sapiens |
? |
- |
? |
| 3.1.3.74 | more |
vitamin B6 metabolism, catabolism of pyridoxal 5-phosphate |
Homo sapiens |
? |
- |
? |
| 3.1.3.74 | more |
enzyme has phosphotransferase activity and transfers 20-25% of the phosphoryl group from either substrate to ethanol |
Homo sapiens |
? |
- |
? |
| 3.1.3.74 | more |
hydrolyzes ten organic phosphates, but has maximum activity against pyridoxal phosphate |
Homo sapiens |
? |
- |
? |
| 3.1.3.74 | more |
specifically dephosphorylates vitamin B6-phosphates, not: phenylphosphate, nucleotide phosphates, such as ATP, ADP, AMP, cAMP, FMN, phosphoamino acids, such as phosphoserine, phosphothreonine, phosphotyrosine, phosphoglycolate |
Homo sapiens |
? |
- |
? |
| 3.1.3.74 | more |
specificity and active site properties, enzyme also catalyzes the dephosphorylation of 4-secondary amine derivatives of vitamin B6 phosphate, enzyme has the greatest catalytic efficiency with substrates that contain a negatively charged group on the 4-position of the pyridine ring, one or two positively charged groups at the active site of enzyme interacts with the substrates phosphate ester and 4-substituent, Arg and His residues are at or near the active site and may play roles in substrate binding and/or catalysis, very low activity with p-nitrophenylphosphate |
Homo sapiens |
? |
- |
? |
