Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 2.7.11.1 - non-specific serine/threonine protein kinase and Organism(s) Rattus norvegicus and UniProt Accession P18266

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nunoue, K.; Ohashi, K.; Okano, I.; Mizuno, K.
LIMK-1 and LIMK-2, two members of a LIM motif-containing protein kinase family
Oncogene
11
701-710
1995
Rattus norvegicus (P53669)
Manually annotated by BRENDA team
O'Donovan, C.; Martin, M.J.; Gattiker, A.; Gasteiger, E.; Bairoch, A.; Apweiler, R.
High quality protein knowledge resources: Swiss-Prot and TrEMBL
Brief. Bioinform.
2
275-284
2002
Rattus norvegicus (Q63802)
-
Manually annotated by BRENDA team
Stephens, L.; Anderson, K.; Stokoe, D.; Erdjument-Bromage, H.; Painter, G.F.; et al.
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
Science
279
710-714
1998
Rattus norvegicus (O55173)
Manually annotated by BRENDA team
Burnett, P.E.; Blackshaw, S.; Lai, M.M.; Qureshi, I.A.; Burnett, A.F.; Sabatini, D.M.; Snyder, S.H.
Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton
Proc. Natl. Acad. Sci. USA
95
8351-8356
1998
Rattus norvegicus (P67999)
Manually annotated by BRENDA team
Kozma, S.C.; Ferrari, S.; Bassand, P.; Siegmann, M.; Totty, N.; Thomas, G.
Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily
Proc. Natl. Acad. Sci. USA
87
7365-7369
1990
Rattus norvegicus (P67999)
Manually annotated by BRENDA team
Harmann, B.; Kilimann, M.W.
cDNA encoding a 59 kDa homolog of ribosomal protein S6 kinase from rabbit liver
FEBS Lett.
273
248-252
1990
Rattus norvegicus (P67999)
Manually annotated by BRENDA team
Banerjee, P.; Ahmad, M.F.; Grove, J.R.; Kozlosky, C.; Price, D.J.; Avruch, J.
Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase
Proc. Natl. Acad. Sci. USA
87
8550-8554
1990
Rattus norvegicus (P67999)
Manually annotated by BRENDA team
Konishi, H.; Shinomura, T.; Kuroda, S.; Ono, Y.; Kikkawa, U.
Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta
Biochem. Biophys. Res. Commun.
205
817-825
1994
Rattus norvegicus (P47196), Rattus norvegicus (P47197)
Manually annotated by BRENDA team
Park, J.; Leong, M.L.; Buse, P.; Maiyar, A.C.; Firestone, G.L.; Hemmings, B.A.
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
EMBO J.
18
3024-3033
1999
Rattus norvegicus (Q06226)
Manually annotated by BRENDA team
Richards, J.S.; Fitzpatrick, S.L.; Clemens, J.W.; Morris, J.K.; Alliston, T.; Sirois, J.
Ovarian cell differentiation: a cascade of multiple hormones, cellular signals, and regulated genes
Recent Prog. Horm. Res.
50
223-254
1995
Rattus norvegicus (Q06226)
Manually annotated by BRENDA team
Imaizumi, K.; Tsuda, M.; Wanaka, A.; Tohyama, M.; Takagi, T.
Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury
Brain Res. Mol. Brain Res.
26
189-196
1994
Rattus norvegicus (Q06226)
Manually annotated by BRENDA team
Webster, M.K.; Goya, L.; Ge, Y.; Maiyar, A.C.; Firestone, G.L.
Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum
Mol. Cell. Biol.
13
2031-2040
1993
Rattus norvegicus (Q06226)
Manually annotated by BRENDA team
Konishi, H.; Kuroda, S.; Tanaka, M.; Matsuzaki, H.; Ono, Y.; Kameyama, K.; Haga, T.; Kikkawa, U.
Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins
Biochem. Biophys. Res. Commun.
216
526-534
1995
Rattus norvegicus (Q63484)
Manually annotated by BRENDA team
Grove, J.R.; Price, D.J.; Banerjee, P.; Balasubramanyam, A.; Ahmad, M.F.; Avruch, J.
Regulation of an epitope-tagged recombinant Rsk-1 S6 kinase by phorbol ester and erk/MAP kinase
Biochemistry
32
7727-7738
1993
Rattus norvegicus (Q63531)
Manually annotated by BRENDA team
Hevroni, D.; Rattner, A.; Bundman, M.; et al.
Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms
J. Mol. Neurosci.
10
75-98
1998
Rattus norvegicus (O08875)
Manually annotated by BRENDA team
Stapleton, D.; Mitchelhill, K.I.; Gao, G.; Widmer, J.; Michell, B.J.; Teh, T.; House, C.M.; Fernandez, C.S.; Cox, T.; Witters, L.A.; Kemp, B.E.
Mammalian AMP-activated protein kinase subfamily
J. Biol. Chem.
271
611-614
1996
Rattus norvegicus (P54645), Homo sapiens (Q13131)
Manually annotated by BRENDA team
Stapleton, D.; Gao, G.; Michell, B.J.; Widmer, J.; Mitchelhill, K.; Teh, T.; House, C.M.; Witters, L.A.; Kemp, B.E.
Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase
J. Biol. Chem.
269
29343-29346
1994
Rattus norvegicus (P54645)
Manually annotated by BRENDA team
Gao, G.; Widmer, J.; Stapleton, D.; Teh, T.; Cox, T.; Kemp, B.E.; Witters, L.A.
Catalytic subunits of the porcine and rat 5'-AMP-activated protein kinase are members of the SNF1 protein kinase family
Biochim. Biophys. Acta
1266
73-82
1995
Rattus norvegicus (Q09137)
Manually annotated by BRENDA team
Carling, D.; Aguan, K.; Woods, A.; Verhoeven, A.J.; Beri, R.K.; Brennan, C.H.; Sidebottom, C.; Davison, M.D.; Scott, J.
Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism
J. Biol. Chem.
269
11442-11448
1994
Rattus norvegicus (Q09137)
Manually annotated by BRENDA team
Hata, Y.; Butz, S.; Sudhof, T.C.
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins
J. Neurosci.
16
2488-2494
1996
Rattus norvegicus (Q62915)
Manually annotated by BRENDA team
Zhang, J.; Gross, S.D.; Schroeder, M.D.; Anderson, R.A.
Casein kinase I alpha and alpha L: alternative splicing-generated kinases exhibit different catalytic properties
Biochemistry
35
16319-16327
1996
Rattus norvegicus (P97633)
Manually annotated by BRENDA team
Graves, P.R.; Haas, D.W.; Hagedorn, C.H.; DePaoli-Roach, A.A.; Roach, P.J.
Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis
J. Biol. Chem.
268
6394-6401
1993
Rattus norvegicus (Q06486)
Manually annotated by BRENDA team
Longenecker, K.L.; Roach, P.J.; Hurley, T.D.
Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition
J. Mol. Biol.
257
618-631
1996
Rattus norvegicus (Q06486)
Manually annotated by BRENDA team
Zhai, L.; Graves, P.R.; Robinson, L.C.; Italiano, M.; Culbertson, M.R.; Rowles, J.; Cobb, M.H.; DePaoli-Roach, A.A.; Roach, P.J.
Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes
J. Biol. Chem.
270
12717-12724
1995
Rattus norvegicus (Q62761), Rattus norvegicus (Q62762), Rattus norvegicus (Q62763)
Manually annotated by BRENDA team
Ahmed, K.; Davis, A.; Hanten, J.; Lambert, D.; McIvor, R.S.; Goueli, S.A.
Cloning of cDNAs encoding the alpha and beta subunits of rat casein kinase 2 (CK-2): investigation of molecular regulation of CK-2 by androgens in rat ventral prostate
Cell. Mol. Biol. Res.
39
451-462
1993
Rattus norvegicus (P19139)
Manually annotated by BRENDA team
Meisner, H.; Heller-Harrison, R.; Buxton, J.; Czech, M.P.
Molecular cloning of the human casein kinase II alpha subunit
Biochemistry
28
4072-4076
1989
Rattus norvegicus (P19139), Homo sapiens (P68400), Homo sapiens
Manually annotated by BRENDA team
Johnston, A.M.; Naselli, G.; Gonez, L.J.; Martin, R.M.; Harrison, L.C.; DeAizpurua, H.J.
SPAK, a STE20/SPS1-related kinase that activates the p38 pathway
Oncogene
19
4290-4297
2000
Rattus norvegicus (O88506), Homo sapiens (Q9UEW8), Mus musculus (Q9Z1W9)
Manually annotated by BRENDA team
Miao, N.; Fung, B.; Sanchez, R.; Lydon, J.; Barker, D.; Pang, K.
Isolation and expression of PASK, a serine/threonine kinase, during rat embryonic development, with special emphasis on the pancreas
J. Histochem. Cytochem.
48
1391-1400
2000
Rattus norvegicus (O88506)
Manually annotated by BRENDA team
Ushiro, H.; Tsutsumi, T.; Suzuki, K.; Kayahara, T.; Nakano, K.
Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
Arch. Biochem. Biophys.
355
233-240
1998
Rattus norvegicus (O88506)
Manually annotated by BRENDA team
Manser, E.; Chong, C.; Zhao, Z.S.; Leung, T.; Michael, G.; Hall, C.; Lim, L.
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
J. Biol. Chem.
270
25070-25078
1995
Rattus norvegicus (P35465), Rattus norvegicus (Q62829)
Manually annotated by BRENDA team
Manser, E.; Leung, T.; Salihuddin, H.; Zhao, Z.S.; Lim, L.
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
Nature
367
40-46
1994
Rattus norvegicus (P35465)
Manually annotated by BRENDA team
Maucuer, A.; Ozon, S.; Manceau, V.; Gavet, O.; Lawler, S.; Curmi, P.; Sobel, A.
KIS is a protein kinase with an RNA recognition motif
J. Biol. Chem.
272
23151-23156
1997
Mus musculus (P97343), Rattus norvegicus (Q63285)
Manually annotated by BRENDA team
Alam, M.R.; Caldwell, B.D.; Johnson, R.C.; Darlington, D.N.; Mains, R.E.; Eipper, B.A.
Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme
J. Biol. Chem.
271
28636-28640
1996
Rattus norvegicus (Q63285)
Manually annotated by BRENDA team
Ohta, S.; Takeuchi, M.; Deguchi, M.; Tsuji, T.; Gahara, Y.; Nagata, K.
A novel transcriptional factor with Ser/Thr kinase activity involved in the transforming growth factor (TGF)-beta signalling pathway
Biochem. J.
350
395-404
2000
Homo sapiens (O75716), Homo sapiens, Mus musculus (O88697), Rattus norvegicus (P57760)
Manually annotated by BRENDA team
Inoue, Y.; Yamamura, H.; Nishizuka, Y.
Protamine kinase independent of adenosine 3,5-monophosphate from rat brain cytosol
Biochem. Biophys. Res. Commun.
50
228-236
1973
Rattus norvegicus
Manually annotated by BRENDA team
Langan, T.A.
Action of adenosine 3,5-monophosphate-dependent histone kinase in vivo
J. Biol. Chem.
244
5763-5765
1969
Rattus norvegicus
Manually annotated by BRENDA team
Baggio, B.; Pinna, L.A.; Moret, V.; Siliprandi, N.
A simple procedure for the purification of rat liver phosvitin kinase
Biochim. Biophys. Acta
207
515-517
1970
Rattus norvegicus
-
Manually annotated by BRENDA team
Wang, Z.; Yang, C.L.; Ellison, D.H.
Comparison of WNK4 and WNK1 kinase and inhibiting activities
Biochem. Biophys. Res. Commun.
317
939-944
2004
Rattus norvegicus
Manually annotated by BRENDA team
Bain, J.; McLauchlan, H.; Elliott, M.; Cohen, P.
The specificities of protein kinase inhibitors: an update
Biochem. J.
371
199-204
2003
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Vitari, A.C.; Deak, M.; Morrice, N.A.; Alessi, D.R.
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
Biochem. J.
391
17-24
2005
Rattus norvegicus
Manually annotated by BRENDA team
Mukai, H.
The structure and function of PKN, a protein kinase having a catalytic domain homologous to that of PKC
J. Biochem.
133
17-27
2003
Asteroidea, Bos taurus, Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus, Xenopus laevis
Manually annotated by BRENDA team
Cavet, M.E.; Lehoux, S.; Berk, B.C.
14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity
J. Biol. Chem.
278
18376-18383
2003
Rattus norvegicus
Manually annotated by BRENDA team
Liu, S.J.; Zhang, J.Y.; Li, H.L.; Fang, Z.Y.; Wang, Q.; Deng, H.M.; Gong, C.X.; Grundke-Iqbal, I.; Iqbal, K.; Wang, J.Z.
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain
J. Biol. Chem.
279
50078-50088
2004
Rattus norvegicus
Manually annotated by BRENDA team
Zhao, X.; Zhuang, S.; Chen, Y.; Boss, G.R.; Pilz, R.B.
Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3
J. Biol. Chem.
280
32683-32692
2005
Rattus norvegicus
Manually annotated by BRENDA team
Coito, C.; Diamond, D.L.; Neddermann, P.; Korth, M.J.; Katze, M.G.
High-throughput screening of the yeast kinome: identification of human serine/threonine protein kinases that phosphorylate the hepatitis C virus NS5A protein
J. Virol.
78
3502-3513
2004
Saccharomyces cerevisiae, Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Takano, A.; Hoe, H.S.; Isojima, Y.; Nagai, K.
Analysis of the expression, localization and activity of rat casein kinase 1epsilon-3
NeuroReport
15
1461-1464
2004
Rattus norvegicus (Q99PS2), Rattus norvegicus (Q9JJ75), Rattus norvegicus (Q9JJ76)
Manually annotated by BRENDA team
Yano, R.; Yap, C.C.; Yamazaki, Y.; Muto, Y.; Kishida, H.; Okada, D.; Hashikawa, T.
Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions
Neuroscience
117
373-381
2003
Rattus norvegicus
Manually annotated by BRENDA team
Min, X.; Lee, B.H.; Cobb, M.H.; Goldsmith, E.J.
Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension
Structure
12
1303-1311
2004
Rattus norvegicus
Manually annotated by BRENDA team
Chao, C.C.; Ma, Y.L.; Lee, E.H.
Protein kinase CK2 impairs spatial memory formation through differential cross talk with PI-3 kinase signaling: activation of Akt and inactivation of SGK1
J. Neurosci.
27
6243-6248
2007
Rattus norvegicus
Manually annotated by BRENDA team
Rafacho, A.; Ribeiro, D.L.; Boschero, A.C.; Taboga, S.R.; Bosqueiro, J.R.
Increased pancreatic islet mass is accompanied by activation of the insulin receptor substrate-2/serine-threonine kinase pathway and augmented cyclin D2 protein levels in insulin-resistant rats
Int. J. Exp. Pathol.
89
264-275
2008
Rattus norvegicus
Manually annotated by BRENDA team
Mao, K.; Kobayashi, S.; Jaffer, Z.M.; Huang, Y.; Volden, P.; Chernoff, J.; Liang, Q.
Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes
J. Mol. Cell. Cardiol.
44
429-434
2008
Mus musculus (P07564), Rattus norvegicus (P35465)
Manually annotated by BRENDA team
Kanan, Y.; Matsumoto, H.; Song, H.; Sokolov, M.; Anderson, R.; Rajala, R.
Serine/threonine kinase Akt activation regulates the activity of retinal serine/threonine phosphatases, PHLPP and PHLPPL
J. Neurochem.
113
477-488
2010
Rattus norvegicus
Manually annotated by BRENDA team
Sahu, A.; Koshinaka, K.; Sahu, M.
Phosphatidylinositol 3-kinase is an upstream regulator of the phosphodiesterase 3B pathway of leptin signalling that may not involve activation of Akt in the rat hypothalamus
J. Neuroendocrinol.
25
168-179
2013
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Manually annotated by BRENDA team
Dong, Q.; Giorgianni, F.; Beranova-Giorgianni, S.; Deng, X.; OMeally, R.; Bridges, D.; Park, E.; Cole, R.; Elam, M.; Raghow, R.
Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation
Biosci. Rep.
36
e00284
2016
Rattus norvegicus (P18266)
Manually annotated by BRENDA team
Schael, S.; Nuechel, J.; Mueller, S.; Petermann, P.; Kormann, J.; Perez-Otano, I.; Martinez, S.; Paulsson, M.; Plomann, M.
Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation
J. Biol. Chem.
288
9303-9312
2013
Mus musculus (O54833), Rattus norvegicus (P19139)
-
Manually annotated by BRENDA team