Reference on EC 2.7.1.127 - inositol-trisphosphate 3-kinase and Organism(s) Homo sapiens and UniProt Accession Q96DU7
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Communi, D.; Vanweyenberg, V.; Erneux, C.
Purification and biochemical properties of a high-molecular-mass inositol 1,4,5-trisphosphate 3-kinase isoenzyme in human platelets
Biochem. J.
298
669-673
1994
Homo sapiens
-
Lin, A.; Wallace, R.W.; Barnes, S.
Purification and properties of a human platelet inositol 1,4,5-trisphosphate 3-kinase
Arch. Biochem. Biophys.
303
412-420
1993
Homo sapiens
Vanweyenberg, V.; Communi, D.; D'Santos, C.S.; Erneux, C.
Tissue- and cell-specific expression of Ins(1,4,5)P3 3-kinase isoenzymes
Biochem. J.
306
429-435
1995
Homo sapiens, Rattus norvegicus
Irvine, R.F.; Schell, M.J.
Back in the water: The return of the inositol phosphates
Nat. Rev. Mol. Cell Biol.
2
327-338
2001
Homo sapiens, Mammalia
Dewaste, V.; Moreau, C.; De Smedt, F.; Bex, F.; De Smedt, H.; Wuytack, F.; Missiaen, L.; Erneux, C.
The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells
Biochem. J.
374
41-49
2003
Homo sapiens
Communi, D.; Vanweyenberg, V.; Erneux, C.
D-myo-inositol 1,4,5-trisphosphate 3-kinase A is activated by receptor activation through a calcium:calmodulin-dependent protein kinase II phosphorylation mechanism
EMBO J.
16
1943-1952
1997
Homo sapiens, Rattus norvegicus
Communi, D.; Dewaste, V.; Erneux, C.
Calcium-calmodulin-dependent protein kinase II and protein kinase C-mediated phosphorylation and activation of D-myo-inositol 1,4, 5-trisphosphate 3-kinase B in astrocytes
J. Biol. Chem.
274
14734-14742
1999
Homo sapiens, Rattus norvegicus
Brehm, M.A.; Schreiber, I.; Bertsch, U.; Wegner, A.; Mayr, G.W.
Identification of the actin-binding domain of Ins(1,4,5)P3 3-kinase isoform B (IP3K-B)
Biochem. J.
382
353-362
2004
Homo sapiens, Rattus norvegicus (P42335)
Xia, H.J.; Yang, G.
Inositol 1,4,5-trisphosphate 3-kinases: functions and regulations
Cell Res.
15
83-91
2005
Drosophila melanogaster, Homo sapiens, Rattus norvegicus, Sus scrofa
Mayr, G.W.; Windhorst, S.; Hillemeier, K.
Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase
J. Biol. Chem.
280
13229-13240
2005
Gallus gallus, Homo sapiens, Rattus norvegicus
Gonzalez, B.; Schell, M.J.; Letcher, A.J.; Veprintsev, D.B.; Irvine, R.F.; Williams, R.L.
Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase
Mol. Cell
15
689-701
2004
Homo sapiens
Nalaskowski, M.M.; Windhorst, S.; Stockebrand, M.C.; Mayr, G.W.
Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains
Biol. Chem.
387
583-593
2006
Homo sapiens, Rattus norvegicus
Mayr, G.W.; Windhorst, S.; Hillemeier, K.
Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase. [Erratum to document cited in CA143:003106]
J. Biol. Chem.
282
35424
2007
Gallus gallus, Homo sapiens (P23677), Homo sapiens (P27987), Rattus norvegicus (Q80ZG2)
-
Windhorst, S.; Fliegert, R.; Blechner, C.; Mollmann, K.; Hosseini, Z.; Gunther, T.; Eiben, M.; Chang, L.; Lin, H.Y.; Fanick, W.; Schumacher, U.; Brandt, B.; Mayr, G.W.
Inositol-1,4,5-trisphosphate-3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumour cells by two functional activities
J. Biol. Chem.
285
5541-5554
2009
Homo sapiens (P23677), Homo sapiens
Windhorst, S.; Minge, D.; Baehring, R.; Hueser, S.; Schob, C.; Blechner, C.; Lin, H.Y.; Mayr, G.W.; Kindler, S.
Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients
Cell. Signal.
24
750-757
2012
Homo sapiens (P23677)
Nalaskowski, M.M.; Fliegert, R.; Ernst, O.; Brehm, M.A.; Fanick, W.; Windhorst, S.; Lin, H.; Giehler, S.; Hein, J.; Lin, Y.N.; Mayr, G.W.
Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope
J. Biol. Chem.
286
4500-4510
2011
Homo sapiens (P27987), Homo sapiens
Erneux, C.; Ghosh, S.; Koenig, S.
Inositol(1,4,5)P3 3-kinase isoenzymes: catalytic properties and importance of targeting to F-actin to understand function
Adv. Biol. Regul.
60
135-143
2016
Homo sapiens (P23677), Homo sapiens (P27987), Homo sapiens (Q96DU7), Homo sapiens, Mus musculus (B2RXC2), Mus musculus (Q7TS72), Mus musculus (Q8R071), Mus musculus, Rattus norvegicus (P17105), Rattus norvegicus (P42335), Rattus norvegicus (Q80ZG2)
Schroeder, D.; Rehbach, C.; Seyffarth, C.; Neuenschwander, M.; Kries, J.V.; Windhorst, S.
Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A
Biochem. Biophys. Res. Commun.
439
228-234
2013
Homo sapiens (P23677)
Franco-Echevarria, E.; Banos-Sanz, J.I.; Monterroso, B.; Round, A.; Sanz-Aparicio, J.; Gonzalez, B.
A new calmodulin-binding motif for inositol 1,4,5-trisphosphate 3-kinase regulation
Biochem. J.
463
319-328
2014
Homo sapiens (P23677), Homo sapiens
Stygelbout, V.; Leroy, K.; Pouillon, V.; Ando, K.; DAmico, E.; Jia, Y.; Luo, H.R.; Duyckaerts, C.; Erneux, C.; Schurmans, S.; Brion, J.P.
Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology
Brain
137
537-552
2014
Homo sapiens (P27987), Homo sapiens, Mus musculus (B2RXC2), Mus musculus
Ashour, D.J.; Pelka, B.; Jaaks, P.; Wundenberg, T.; Blechner, C.; Zobiak, B.; Failla, A.V.; Windhorst, S.
The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin
Cytoskeleton (Hoboken)
72
93-100
2015
Homo sapiens (P23677)
Windhorst, S.; Song, K.; Gazdar, A.F.
Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) is frequently over-expressed and functions as an oncogene in several tumor types
Biochem. Pharmacol.
137
1-9
2017
Homo sapiens (P23677), Homo sapiens, Mus musculus (Q8R071)
Wei, R.; Cao, G.; Deng, Z.; Su, J.; Cai, L.
miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells
Biosci. Rep.
36
art:e00392
2016
Homo sapiens (P27987), Homo sapiens
