Reference on EC 2.7.1.105 - 6-phosphofructo-2-kinase and Organism(s) Rattus norvegicus and UniProt Accession P07953
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Loiseau, A.M.; Rider, M.H.; Hue, L.
Purification and properties of 6-phosphofructo-2-kinase and fructose-2,6-bisphosphatase from rat hepatoma cells
Biochem. Soc. Trans.
15
384-385
1987
Rattus norvegicus
-
El-Maghrabi, M.R.; Correia, J.J.; Heil, P.J.; Pate, T.M.; Cobb, C.E.; Pilkis, S.J.
Tissue distribution, immunoreactivity, and physical properties of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Proc. Natl. Acad. Sci. USA
83
5005-5009
1986
Bos taurus, Canis lupus familiaris, Rattus norvegicus
Sakurai, T.; Johnson, J.H.; Uyeda, K.
Islet fructose 6-phosphate, 2-kinase: fructose 2,6-bisphosphatase: isozymic form, expression, and characterization
Biochem. Biophys. Res. Commun.
218
159-163
1996
Bos taurus, Rattus norvegicus
Van Schaftingen, E.; Hers, H.G.
Phosphofructokinase 2: the enzyme that forms fructose 2,6-bisphosphate from fructose 6-phosphate and ATP
Biochem. Biophys. Res. Commun.
101
1078-1084
1981
Rattus norvegicus
El-Maghrabi, M.R.; Claus, T.H.; Pilkis, J.; Pilkis, S.J.
Partial purification of a rat liver enzyme that catalyzes the formation of fructose 2,6-bisphosphate
Biochem. Biophys. Res. Commun.
101
1071-1077
1981
Rattus norvegicus
El-Maghrabi, M.R.; Fox, E.; Pilkis, J.; Pilkis, S.J.
Cyclic AMP-dependent phosphorylation of rat liver 6-phosphofructo 2-kinase, fructose 2,6-bisphosphatase
Biochem. Biophys. Res. Commun.
106
794-802
1982
Rattus norvegicus
Kretschmer, M.; Hofmann, E.
Inhibition of rat liver phosphofructokinase-2 by phosphoenolpyruvate and ADP
Biochem. Biophys. Res. Commun.
124
793-796
1984
Rattus norvegicus
Sakakibara, R.; Kitajima, S.; Uyeda, K.
Differences in kinetic properties of phospho and dephospho forms of fructose-6-phosphate, 2-kinase and fructose 2,6-bisphosphatase
J. Biol. Chem.
259
41-46
1984
Rattus norvegicus
Pilkis, S.J.; Regen, D.M.; Stewart, H.B.; Pilkis, J.; Pate, T.M.; El-Maghrabi, M.R.
Evidence for two catalytic sites on 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase. Dynamics of substrate exchange and phosphoryl enzyme formation
J. Biol. Chem.
259
949-958
1984
Rattus norvegicus
Kitajima, S.; Sakakibara, R.; Uyeda, K.
Kinetic studies of fructose 6-phosphate,2-kinase and fructose 2,6-bisphosphatase
J. Biol. Chem.
259
6896-6903
1984
Rattus norvegicus
Laloux, M.; Van Schaftingen, E.; Francois, J.; Hers, H.G.
Phosphate dependency of phosphofructokinase 2
Eur. J. Biochem.
148
155-159
1985
Saccharomyces cerevisiae, Rattus norvegicus, Spinacia oleracea
Sakakibara, R.; Tanaka, T.; Uyeda, K.; Richards, E.G.; Thomas, H.
Studies of the structure of fructose-6-phosphate 2-kinase:fructose-2,6-bisphosphatase
Biochemistry
24
6818-6824
1985
Rattus norvegicus
Kountz, P.D.; McCain, R.W.; El-Maghrabi, M.R.; Pilkis, S.J.
Hepatic 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase: phosphate dependence and effects of other oxyanions
Arch. Biochem. Biophys.
251
110-113
1986
Rattus norvegicus
-
Lively, M.O.; El-Maghrabi, M.R.; Pilkis, J.; D'Angelo, G.; Colosia, A.D.; Ciavola, J.A.; Fraser, B.A.; Pilkis, S.J.
Complete amino acid sequence of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
J. Biol. Chem.
263
839-849
1988
Rattus norvegicus
Martn-Sanz, P.; Cascales, M.; Bosc, L.
Characterization of 6-phosphofructo-2-kinase from foetal-rat liver
Biochem. J.
281
457-463
1992
Rattus norvegicus
-
Van Schaftingen, E.; Davies, D.R.; Hers, H.G.
Inactivation of phosphofructokinase 2 by cyclic AMP - dependent protein kinase
Biochem. Biophys. Res. Commun.
103
362-368
1981
Rattus norvegicus
Kitamura, K.; Uyeda, K.; Kangawa, K.; Matsuo, H.
Purification and characterization of rat skeletal muscle fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
J. Biol. Chem.
264
9799-9806
1989
Rattus norvegicus
Pilkis, S.J.; Pilkis, J.; El-Maghrabi, M.R.; Claus, T.H.
The sugar phosphate specificity of rat hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
J. Biol. Chem.
260
7551-7556
1985
Rattus norvegicus
Rider, M.H.; Foret, D.; Hue, L.
Comparison of purified bovine heart and rat liver 6-phosphofructo-2-kinase. Evidence for distinct isoenzymes
Biochem. J.
231
193-196
1985
Bos taurus, Rattus norvegicus
Kountz, P.D.; El-Maghrabi, M.R.; Pilkis, S.J.
Isolation and characterization of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from bovine liver
Arch. Biochem. Biophys.
238
531-543
1985
Bos taurus, Rattus norvegicus
Rider, M.H.; Vandamme, J.; Lebeau, E.; Vertommen, D.; Vidal, H.; Rousseau, G.G.; Vanderkerkhove, J.; Hue, L.
The two forms of bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase result from alternative splicing
Biochem. J.
285
405-411
1992
Bos taurus, Rattus norvegicus
-
Kitamura, K.; Uyeda, K.
Purification and characterization of myocardial fructose-6-phosphate,2-kinase and fructose-2,6-bisphosphatase [published erratum appears in J Biol Chem 1989 Jan 25;264(3):1901]
J. Biol. Chem.
263
9027-9033
1988
Bos taurus, Rattus norvegicus
Lange, A.J.; Li, L.; Vargas, A.M.; Pilkis, S.J.
Expression of human liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in Escherichia coli. Role of N-2 proline in degradation of the protein
J. Biol. Chem.
268
8078-8084
1993
Homo sapiens, Rattus norvegicus
Rider, M.H.
Regulation of fructose-2,6-bisphosphate synthesis and breakdown in heart and skeletal muscle
Biochem. Soc. Trans.
15
988-991
1987
Bos taurus, Columba sp., Rattus norvegicus
Li, L.; Lange, A.J.; Pilkis, S.J.
Isolation of a cDNA for chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase [published erratum appears in Biochem Biophys Res Commun 1999 Jun 16;259(3):711]
Biochem. Biophys. Res. Commun.
190
397-405
1993
Gallus gallus, Rattus norvegicus
Rider, M.H.; Hue, L.
Bifunctionality of muscle and heart 6-phosphofructo-2-kinase: skeletal muscle 6-phosphofructo-2-kinase catalyses fructose 2,6-bisphosphate hydrolysis whereas heart 6-phophofructo-2-kinase contains little fructose-2,6-bisphphophatase
Biochem. Soc. Trans.
15
379-380
1987
Rattus norvegicus
-
Kurland, I.J.; Chapman, B.; El-Maghrabi, M.R.
N- and C-termini modulate the effects of pH and phosphorylation on hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Biochem. J.
347
459-467
2000
Escherichia coli, Rattus norvegicus
Hasemann, C.A.; Istvan, E.S.; Uyeda, K.; Deisenhofer, J.
The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies
Structure
4
1017-1029
1996
Rattus norvegicus
Watanabe, F.; Jameson, D.M.; Uyeda, K.
Enzymic and fluorescence studies of four single-tryptophan mutants of rat testis fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase
Protein Sci.
5
904-913
1996
Rattus norvegicus
Mizuguchi, H.; Cook, P.F.; Hasemann, C.A.; Uyeda, K.
Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues
Biochemistry
36
8775-8784
1997
Rattus norvegicus
Tominaga, N.; Tsujikawa, T.; Minami, Y.; Wu, R.F.; Watanabe, F.; Sakakibara, R.; Uyeda, K.
Effect of replacement of the amino and the carboxyl termini of rat testis fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase with those of the liver and heart isozymes
Arch. Biochem. Biophys.
347
275-281
1997
Bos taurus, Rattus norvegicus
Yuen, M.H.; Wang, X.L.; Mizuguchi, H.; Uyeda, K.; Hasemann, C.A.
A switch in the kinase domain of rat testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Biochemistry
38
12333-12342
1999
Rattus norvegicus (P25114)
Sakakibara, R.; Okudaira, T.; Fujiwara, K.; Kato, M.; Hirata, T.; Yamanaka, S.; Naito, M.; Fukasawa, M.
Tissue distribution of placenta-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Biochem. Biophys. Res. Commun.
257
177-181
1999
Homo sapiens, Rattus norvegicus
Harada, Y.; Tominaga, N.; Watanabe, M.; Shimokawa, R.; Ishiguro, M.; Sakakibara, R.
Inhibition of fructose-6-phosphate,2-kinase by N-bromoacetylethanolamine phosphate in vitro and in vivo
J. Biochem.
121
724-730
1997
Mus musculus, Rattus norvegicus
Zhu, Z.; Ling, S.; Yang, Q.H.; Li, L.
Involvement of the chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase sequence His444-Arg-Glu-Arg in modulation of the bisphosphatase activity by its kinase domain
Biochem. J.
357
513-520
2001
Gallus gallus, Rattus norvegicus
Bruni, P.; Vandoolaeghe, P.; Rousseau, G.G.; Hue, L.; Rider, M.H.
Expression and regulation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isozymes in white adipose tissue
Eur. J. Biochem.
259
756-761
1999
Rattus norvegicus
Goldstein, B.N.; Maevsky, A.A.
Critical switch of the metabolic fluxes by phosphofructo-2-kinase:fructose-2,6-bisphosphatase. A kinetic model
FEBS Lett.
532
295-299
2002
Rattus norvegicus
Payne, V.A.; Arden, C.; Wu, C.; Lange, A.J.; Agius, L.
Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes
Diabetes
54
1949-1957
2005
Rattus norvegicus
Payne, V.A.; Arden, C.; Lange, A.J.; Agius, L.
Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats
Am. J. Physiol. Regul. Integr. Comp. Physiol.
293
R618-R625
2007
Rattus norvegicus
Kim, S.G.; Cavalier, M.; El-Magrabi, M.R.; Lee, Y.M.
A direct substratesubstrate interaction found in the kinase domain of the bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
J. Biol. Chem.
370
14-26
2007
Rattus norvegicus
Smith, W.E.; Langer, S.; Wu, C.; Baltrusch, S.; Okar, D.A.
Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase:glucokinase complex
Mol. Endocrinol.
21
1478-1487
2007
Rattus norvegicus
Mukhtar, M.H.; Payne, V.A.; Arden, C.; Harbottle, A.; Khan, S.; Lange, A.J.; Agius, L.
Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Am. J. Physiol. Regul. Integr. Comp. Physiol.
294
R766-R774
2008
Rattus norvegicus (Q9JJH5)
Mykhalchenko, V.G.; Minchenko, D.O.; Tsuchihara, K.; Moenner, M.; Komisarenko, S.V.; Bikfalvi, A.; Esumi, H.; Minchenko, O.H.
Expression of mouse 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 mRNA alternative splice variants in hypoxia
Ukr. Biokhim. Zh.
80
19-25
2008
Rattus norvegicus (A7UAK3), Mus musculus (A7UAK4), Mus musculus (A7UAK5), Mus musculus (A7UAK6), Mus musculus
Gomez, M.; Navarro-Sabate, A.; Manzano, A.; Duran, J.; Obach, M.; Bartrons, R.
Switches in 6-phosphofructo-2-kinase isoenzyme expression during rat sperm maturation
Biochem. Biophys. Res. Commun.
387
330-335
2009
Rattus norvegicus
Langer, S.; Kaminski, M.T.; Lenzen, S.; Baltrusch, S.
Endogenous activation of glucokinase by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is glucose dependent
Mol. Endocrinol.
24
1988-1997
2010
Rattus norvegicus
Baltrusch, S.; Schmitt, H.; Brix, A.; Langer, S.; Lenzen, S.
Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260
Biochem. Pharmacol.
83
1300-1306
2012
Rattus norvegicus
Langer, S.; Okar, D.A.; Schultz, J.; Lenzen, S.; Baltrusch, S.
Dimer interface rearrangement of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase rat liver isoenzyme by cAMP-dependent Ser-32 phosphorylation
FEBS Lett.
586
1419-1425
2012
Rattus norvegicus (P07953)
Novellasdemunt, L.; Tato, I.; Navarro-Sabate, A.; Ruiz-Meana, M.; Mendez-Lucas, A.; Perales, J.C.; Garcia-Dorado, D.; Ventura, F.; Bartrons, R.; Rosa, J.L.
Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids
J. Biol. Chem.
288
10640-10651
2013
Homo sapiens (O60825), Homo sapiens, Rattus norvegicus (Q9JJH5), Rattus norvegicus Sprague-Dawley (Q9JJH5)
Cullen, K.S.; Al-Oanzi, Z.H.; OHarte, F.P.; Agius, L.; Arden, C.
Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein
Biochim. Biophys. Acta
1843
1123-1134
2014
Rattus norvegicus (P07953), Rattus norvegicus Wistar (P07953)
