EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
2.7.1.105 | 749813 |
6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor beta1-enhanced invasion of Panc1 cells invitro |
Biochem. Biophys. Res. Commun. |
484 |
687-693 |
2017 |
Homo sapiens |
28161638 |
2.7.1.105 | 761915 |
6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4 A pair of valves for fine-tuning of glucose metabolism in human cancer |
Mol. Metab. |
20 |
1-13 |
2019 |
Homo sapiens |
30553771 |
2.7.1.105 | 751761 |
6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells |
Oncogene |
36 |
3287-3299 |
2017 |
Homo sapiens |
28092678 |
2.7.1.105 | 760902 |
6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase-2 regulates TP53-dependent paclitaxel sensitivity in ovarian and breast cancers |
Clin. Cancer Res. |
25 |
5702-5716 |
2019 |
Homo sapiens |
31391192 |
2.7.1.105 | 760543 |
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase and small chemical activators affect enzyme activity of activating glucokinase mutants by distinct mechanisms |
Biochem. Pharmacol. |
168 |
149-161 |
2019 |
Homo sapiens |
31254492 |
2.7.1.105 | 751774 |
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway |
Oncotarget |
8 |
80909-80922 |
2017 |
Homo sapiens |
29113354 |
2.7.1.105 | 752141 |
Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding |
Proteins |
85 |
117-124 |
2017 |
Homo sapiens |
27802586 |
2.7.1.105 | 752141 |
Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding |
Proteins |
85 |
117-124 |
2017 |
Bos taurus |
27802586 |
2.7.1.105 | 761491 |
Increased 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 activity in response to EGFR signaling contributes to non-small cell lung cancer cell survival |
J. Biol. Chem. |
294 |
10530-10543 |
2019 |
Homo sapiens |
31126985 |
2.7.1.105 | 749587 |
Inhibition of growth by combined treatment with inhibitors of lactate dehydrogenase and either phenformin or inhibitors of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 |
Anticancer Res. |
36 |
1479-1488 |
2016 |
Homo sapiens |
27069123 |