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Reference on EC 2.3.1.298 - ultra-long-chain ceramide synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mizutani, Y.; Kihara, A.; Igarashi, Y.
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
Biochem. J.
398
531-538
2006
Mus musculus (Q1A3B0)
Manually annotated by BRENDA team
Park, J.; Park, W.; Futerman, A.
Ceramide synthases as potential targets for therapeutic intervention in human diseases
Biochim. Biophys. Acta
1841
671-681
2014
Mus musculus
Manually annotated by BRENDA team
Holmes, R.S.; Barron, K.A.; Krupenko, N.I.
Ceramide synthase 6 comparative analysis, phylogeny and evolution
Biomolecules
8
111
2018
Danio rerio (A0A140LFW4), Gallus gallus (F1N8P2), Mus musculus (Q1A3B0), Homo sapiens (Q8IU89)
Manually annotated by BRENDA team
Jensen, J.M.; Forl, M.; Winoto-Morbach, S.; Seite, S.; Schunck, M.; Proksch, E.; Schutze, S.
Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging
Exp. Dermatol.
14
609-618
2005
Mus musculus (Q1A3B0), Mus musculus SKH-1 (Q1A3B0)
Manually annotated by BRENDA team
Georgopapadakou, N.
Antifungals targeted to sphingolipid synthesis Focus on inositol phosphorylceramide synthase
Expert Opin. Investig. Drugs
9
1787-1796
2000
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Sandhoff, R.
Very long chain sphingolipids tissue expression, function and synthesis
FEBS Lett.
584
1907-1913
2010
Mus musculus
Manually annotated by BRENDA team
Jennemann, R.; Rabionet, M.; Gorgas, K.; Epstein, S.; Dalpke, A.; Rothermel, U.; Bayerle, A.; van der Hoeven, F.; Imgrund, S.; Kirsch, J.; Nickel, W.; Willecke, K.; Riezman, H.; Groene, H.J.; Sandhoff, R.
Loss of ceramide synthase 3 causes lethal skin barrier disruption
Hum. Mol. Genet.
21
586-608
2012
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Rabionet, M.; Bayerle, A.; Jennemann, R.; Heid, H.; Fuchser, J.; Marsching, C.; Porubsky, S.; Bolenz, C.; Guillou, F.; Groene, H.J.; Gorgas, K.; Sandhoff, R.
Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors
Hum. Mol. Genet.
24
4792-4808
2015
Mus musculus
Manually annotated by BRENDA team
Sassa, T.; Hirayama, T.; Kihara, A.
Enzyme activities of the ceramide synthases CERS2-6 are regulated by phosphorylation in the C-terminal region
J. Biol. Chem.
291
7477-7487
2016
Homo sapiens
Manually annotated by BRENDA team
Ferreira, N.S.; Engelsby, H.; Neess, D.; Kelly, S.L.; Volpert, G.; Merrill, A.H.; Futerman, A.H.; Faergeman, N.J.
Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein
J. Biol. Chem.
292
7588-7597
2017
Mus musculus
Manually annotated by BRENDA team
Mizutani, Y.; Kihara, A.; Chiba, H.; Tojo, H.; Igarashi, Y.
2-Hydroxy-ceramide synthesis by ceramide synthase family enzymatic basis for the preference of FA chain length
J. Lipid Res.
49
2356-2364
2008
Homo sapiens, Homo sapiens (Q8IU89)
Manually annotated by BRENDA team
Lim, X.Y.; Pickford, R.; Don, A.S.
Assaying ceramide synthase activity in vitro and in living cells using liquid chromatography-mass spectrometry
Methods Mol. Biol.
1376
11-22
2016
Homo sapiens (Q8IU89)
Manually annotated by BRENDA team
Mizutani, Y.; Sun, H.; Ohno, Y.; Sassa, T.; Wakashima, T.; Obara, M.; Yuyama, K.; Kihara, A.; Igarashi, Y.
Cooperative synthesis of ultra long-chain fatty acid and ceramide during keratinocyte differentiation
PLoS ONE
8
e67317
2013
Homo sapiens, Mus musculus
Manually annotated by BRENDA team