6.3.2.5: phosphopantothenate-cysteine ligase (CTP)

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For detailed information about phosphopantothenate-cysteine ligase (CTP), go to the full flat file.

Reaction

Synonyms

4�-phosphopantothenoylcysteine synthetase, CoaB, CoaBC, coupling enzyme, Dfp, pantothenate 4�-phosphate:L-cysteine ligase, phosphopantothenate-cysteine ligase, phosphopantothenoyl-cysteine ligase, phosphopantothenoylcysteine synthetase, PPC synthase, PPC synthetase, PPC-S, PPCS, synthetase, phosphopantothenoylcysteine

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.5 phosphopantothenate-cysteine ligase (CTP)

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Results	in table
35953	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
3	Cofactor
2	Crystallization (Commentary)
11	Disease/ Diagnostics
3	General Information
14	Inhibitors
7	Ki Value [mM]
20	KM Value [mM]
2	Metals/Ions
6	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
27	Organism
6	Pathway
34	PDB ID
2	pH Optimum
18	Protein Variants
8	Purification (Commentary)
6	Reaction
2	Reaction Type
27	Reference
8	Source Tissue
3	Specific Activity [micromol/min/mg]
38	Substrates and Products (Substrate)
7	Subunits
27	Synonyms
1	Systematic Name
5	Turnover Number [1/s]

Cloned

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Cloned on EC 6.3.2.5 - phosphopantothenate-cysteine ligase (CTP)

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expressed in Escherichia coli M15 (pREP4) cells

Methanocaldococcus jannaschii

Q58323

674749

expressed in Escherichia coli Tuner(DE3) cells

Escherichia coli

-

648960

expression in Escherichia coli

2 entries

overexpression in Escherichia coli

Methanocaldococcus jannaschii

Q58323

674749

expression in Escherichia coli

Homo sapiens

-

702454

expression in Escherichia coli

Enterococcus faecalis

-

702284