6.1.1.7: alanine-tRNA ligase

This is an abbreviated version!
For detailed information about alanine-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.7

6.1.1.7

aminoacylation

synthetases

aminoacyl-trna

leukodystrophy

alanylation

mischarged

aarss

leukoencephalopathy

mistranslation

tmrnas

charcot-marie-tooth

noncognate

thrrs

threonyl-trna

minihelix

seryl-trna

anti-pl-12

valrs

misactivation

microhelix

ilers

trans-translation

molecular biology

Reaction

Synonyms

AARS2, Ala-tRNA synthetase, ALA1, ALA2, Alanine transfer RNA synthetase, Alanine translase, Alanine tRNA synthetase, Alanine--tRNA ligase, Alanine-transfer RNA ligase, alanine-tRNA ligase, alanyl tRNA ligase, Alanyl-transfer ribonucleate synthetase, Alanyl-transfer ribonucleic acid synthetase, Alanyl-transfer RNA synthetase, alanyl-tRNA ligase, alanyl-tRNA synthase, Alanyl-tRNA synthetase, alanyltRNA synthetase, AlaRS, mitochondrial alanyl-tRNA synthetase, More, mtAlaRS, MurM, MurN, Synthase, alanyl-transfer ribonucleate

ECTree

6 Ligases

6.1 Forming carbon-oxygen bonds

6.1.1 Ligases forming aminoacyl-tRNA and related compounds

6.1.1.7 alanine-tRNA ligase

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Results	in table
6	Activating Compound
56313	AA Sequence
2	Application
1	CAS Registry Number
29	Cloned(Commentary)
18	Cofactor
9	Crystallization (Commentary)
151	Disease/ Diagnostics
4	Expression
18	General Information
2	General Stability
16	Inhibitors
1	kcat/KM [mM/s]
2	Ki Value [mM]
57	KM Value [mM]
24	Localization
17	Metals/Ions
23	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
159	Organism
4	Pathway
70	PDB ID
14	pH Optimum
1	pH Range
51	Protein Variants
24	Purification (Commentary)
2	Reaction
20	Reaction Type
61	Reference
2	Renatured (Commentary)
8	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
79	Substrates and Products (Substrate)
21	Subunits
176	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
3	Temperature Range [°C]
3	Temperature Stability [°C]
38	Turnover Number [1/s]

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79 - 120

ATP

8 entries

0.0035 - 3.7

glycine

4 entries

0.0074 - 1.4

L-alanine

4 entries

0.0028 - 2.4

L-serine

3 entries

0.0635 - 0.071

lipid II L-Ala

2 entries

0.0166

lipid II L-Ser

2 entries

0.043 - 0.1

tmRNA

2 entries

0.19 - 2.2

tRNAAla

9 entries

0.25

tRNAPhe

Escherichia coli

native dual specific tRNAPhe substrate from Saccharomyces cerevisiae, pH 7.5, 37°C

650000

0.25

tRNAPhe(17)

Escherichia coli

tRNAPhe mutant tRNAPhe(17), pH 7.5, 37°C

650000

0.46

tRNAPhe(38)

Escherichia coli

tRNAPhe mutant tRNAPhe(38), pH 7.5, 37°C

650000

0.12

tRNAPhe(57)

Escherichia coli

tRNAPhe mutant tRNAPhe(57), pH 7.5, 37°C

650000