5.4.99.B22: multisite-specific tRNA pseudouridine synthase

This is an abbreviated version!
For detailed information about multisite-specific tRNA pseudouridine synthase, go to the full flat file.

Word Map on EC 5.4.99.B22

5.4.99.B22

pseudouridylation

anemia

sideroblastic

myopathy

dyskerin

anticodon

mlasa

spliceosomal

nuclear-encoded

agriculture

Reaction

Synonyms

cePus1p, dmPus1p, hPus1p, mPus1p, pseudouridine synthase 1, pseudouridine synthase Pus10, PUS1, Pus1p, Pus4, PUS6, PUS7, RluE, RNA:pseudouridine synthases 1, RPUSD4, scPus1p, spPus1p, SVR1, TgPUS1, xtPus1p, YmfC

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.99 Transferring other groups

5.4.99.B22 multisite-specific tRNA pseudouridine synthase

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Results	in table
15	AA Sequence
1	Application
13	Cloned(Commentary)
2	Crystallization (Commentary)
21	Disease/ Diagnostics
48	General Information
2	Inhibitors
2	kcat/KM [mM/s]
4	KM Value [mM]
3	Localization
2	Metals/Ions
15	Natural Substrates/ Products (Substrates)
109	Organism
2	pH Optimum
24	Protein Variants
11	Purification (Commentary)
18	Reaction
33	Reference
7	Source Tissue
67	Substrates and Products (Substrate)
2	Subunits
51	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 5.4.99.B22 - multisite-specific tRNA pseudouridine synthase

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EDTA

Saccharomyces cerevisiae

Q12211

the complex Pus1/tRNAVal is sensitive to the presence of EDTA

5860

KCl

Saccharomyces cerevisiae

Q12211

the complex of Pus1 with tRNA is sensitive to high ionic strength. The optimal concentration of KCl for Pus1 binding is 100 mM. Above 400 mM KCl, no complex is detected

5860