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4.2.3.3: methylglyoxal synthase

This is an abbreviated version!
For detailed information about methylglyoxal synthase, go to the full flat file.

Word Map on EC 4.2.3.3

Reaction

glycerone phosphate
=
2-oxopropanal
+
phosphate

Synonyms

EC 4.2.99.11, methylglyoxal synthase, methylglyoxal synthetase, MGS, MgsA, msgA, synthase, methylglyoxal

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.3 methylglyoxal synthase

General Stability

General Stability on EC 4.2.3.3 - methylglyoxal synthase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
D71N mutant enzyme rapidly becomes inactive in the absence of phosphate
-
dihydroxyacetone phosphate or bovine serum albumin stabilizes
-
phosphate stabilizes towards both cold-induced inactivation and against heat-induced inactivation
-
removal of phosphate from the purified enzyme leads to rapid loss of activity, which is more pronounced at 0°C than at 22°C. Dihydroxyacetone phosphate and bovine serum albumin overcome the inactivation to some extent
-