4.1.3.1: isocitrate lyase

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For detailed information about isocitrate lyase, go to the full flat file.

Word Map on EC 4.1.3.1

4.1.3.1

interstrand

malate

lens

eyes

collamer

postoperative

intraocular

crosslinks

refract

preoperative

phakic

acuity

fanconi

anemia

posterior

spherical

uncorrected

myopic

vault

fork

diopter

corneal

astigmatism

glyoxysomal

fancd2

pupil

lymphocytopenia

translesion

logmar

itaconate

anaplerotic

monoubiquitination

psoralens

monoadducts

gaba-induced

vision-threatening

pupillary

incisions

hyperopic

keratomileusis

subcapsular

lasik

microbodies

biomicroscopy

drug development

snellen

medicine

as-oct

best-corrected

sn-glycerol-3-phosphate

spectacle

molecular biology

gelatinosa

Reaction

Synonyms

AceA, acuD, citrate lyase, D-threo-isocitrate: glyoxylate lyase, EgGCE, FPICL1, ICL, ICL1, ICL2, isocitrase, isocitratase, isocitrate lyase, isocitrate lyase 1, isocitrate lyase 2, isocitric lyase, isocitritase, lyase, isocitrate, MtbIcl, PDP, petal death protein, SSO1333, threo-DS-Isocitrate glyoxylate-lyase

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.3 Oxo-acid-lyases

4.1.3.1 isocitrate lyase

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Results	in table
42	Activating Compound
16957	AA Sequence
15	Application
1	CAS Registry Number
45	Cloned(Commentary)
8	Crystallization (Commentary)
19	Expression
61	General Information
4	General Stability
120	IC50 Value
523	Inhibitors
5	kcat/KM [mM/s]
24	Ki Value [mM]
130	KM Value [mM]
18	Localization
95	Metals/Ions
114	Molecular Weight [Da]
98	Natural Substrates/ Products (Substrates)
822	Organism
3	Oxidation Stability
7	Pathway
118	PDB ID
56	pH Optimum
8	pH Range
4	pH Stability
3	pI Value
4	Posttranslational Modification
63	Protein Variants
72	Purification (Commentary)
4	Reaction
2	Reaction Type
210	Reference
59	Source Tissue
80	Specific Activity [micromol/min/mg]
31	Storage Stability
235	Substrates and Products (Substrate)
72	Subunits
208	Synonyms
1	Systematic Name
27	Temperature Optimum [°C]
4	Temperature Range [°C]
37	Temperature Stability [°C]
31	Turnover Number [1/s]

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1.25

(2R,3S:2S,3R)-2-methyl-isocitrate

Mycobacterium tuberculosis

P9WKK7

ICL1, in 50 mM MOPS pH 6.8, 5 mM MgCl2

681995

18.1 - 32

DL-isocitrate

2 entries

3.6

glyoxylate

Mycobacterium tuberculosis

pH 7.5, 25°C, recombinant enzyme

727039

0.56 - 800

isocitrate

20 entries

3.6 - 8.5

succinate

2 entries

7.53 - 9.78

threo-DL-Isocitrate

4 entries

threo-Ds-isocitrate

Bacillus sp. (in: Bacteria)

33135