Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.1.3.1: isocitrate lyase

This is an abbreviated version!
For detailed information about isocitrate lyase, go to the full flat file.

Word Map on EC 4.1.3.1

Reaction

isocitrate
=
succinate
+
glyoxylate

Synonyms

AceA, acuD, citrate lyase, D-threo-isocitrate: glyoxylate lyase, EgGCE, FPICL1, ICL, ICL1, ICL2, isocitrase, isocitratase, isocitrate lyase, isocitrate lyase 1, isocitrate lyase 2, isocitric lyase, isocitritase, lyase, isocitrate, MtbIcl, PDP, petal death protein, SSO1333, threo-DS-Isocitrate glyoxylate-lyase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.1 isocitrate lyase

KI Value

KI Value on EC 4.1.3.1 - isocitrate lyase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.003 - 0.11
3-nitropropionate
0.12 - 0.71
Bromopyruvate
0.06
D-fructose-6-phosphate
-
-
0.3
D-Glucose-6-phosphate
-
-
4.3
glyoxylate
-
recombinant detagged enzyme, pH 7.0, 37°C
0.5
Hydroxymalonate
-
-
0.0119 - 0.22
Itaconate
0.19 - 0.48
itaconic anhydride
1
malate
-
-
15
methylmalonate
-
-
5
oxalacetate
-
-
0.037
oxalate
-
pH 7
0.893
phosphoenolpyruvate
-
in 100 mM potassium phosphate buffer (pH 7.1), 10 mM MgCl2, 12 mM cysteine
1.8
succinate
-
-
additional information
additional information
-
solvent isotope effects in inhibition by itaconate and 3-nitropropionate, overview
-