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4.1.3.1: isocitrate lyase

This is an abbreviated version!
For detailed information about isocitrate lyase, go to the full flat file.

Word Map on EC 4.1.3.1

Reaction

isocitrate
=
succinate
+
glyoxylate

Synonyms

AceA, acuD, citrate lyase, D-threo-isocitrate: glyoxylate lyase, EgGCE, FPICL1, ICL, ICL1, ICL2, isocitrase, isocitratase, isocitrate lyase, isocitrate lyase 1, isocitrate lyase 2, isocitric lyase, isocitritase, lyase, isocitrate, MtbIcl, PDP, petal death protein, SSO1333, threo-DS-Isocitrate glyoxylate-lyase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.1 isocitrate lyase

Crystallization

Crystallization on EC 4.1.3.1 - isocitrate lyase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
complexed with glyoxylate and a divalent cation
-
hanging drop vapor diffusion method
-
complexed with Mn2+ and malonate, sitting drop vapor diffusion method, using 2.4 M sodium malonate
vapour diffusion with 0.1 M Tris-HCl, 0.2 M sodium acetate, 20-30% (w/v) PEG 4000, pH 8.0
ligand-free form and as a complex with Mg2+, glyoxylate, and glycerol, sitting drop vapor diffusion method, using 0.2 M sodium malonate and 20% (w/v) PEG 3350 or 0.2 M potassium sodium tartrate and 10% (v/v) glycerol