4.1.1.21: phosphoribosylaminoimidazole carboxylase

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For detailed information about phosphoribosylaminoimidazole carboxylase, go to the full flat file.

Word Map on EC 4.1.1.21

4.1.1.21

saicars

n5-cair

phosphoribosylaminoimidazolesuccinocarboxamide

4-carboxy-5-aminoimidazole

6.3.2.6

aircs

n5-carboxyaminoimidazole

samdc

analysis

Reaction

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-D-ribosyl)imidazole

Synonyms

5-Amino-1-ribosylimidazole 5-phosphate carboxylase, 5-Phosphoribosyl-5-aminoimidazole carboxylase, AdeD, AIR carboxylase, AIRC, aminoimidazole ribonucleotide carboxylase, Carboxylyase, phosphoribosylaminoimidazole, class II PurE, PAICS, phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, PurE

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.1 Carboxy-lyases

4.1.1.21 phosphoribosylaminoimidazole carboxylase

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Results	in table
3213	AA Sequence
1	Application
1	CAS Registry Number
8	Cloned(Commentary)
4	Crystallization (Commentary)
1	General Stability
1	IC50 Value
11	Inhibitors
2	kcat/KM [mM/s]
7	Ki Value [mM]
5	KM Value [mM]
13	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
21	Organism
6	Pathway
139	PDB ID
1	pH Stability
2	pI Value
4	Protein Variants
7	Purification (Commentary)
1	Reaction
2	Reaction Type
21	Reference
5	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
24	Substrates and Products (Substrate)
7	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Stability [°C]
4	Turnover Number [1/s]

Purification

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Purification on EC 4.1.1.21 - phosphoribosylaminoimidazole carboxylase

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3 entries

bifunctional protein complex possessing phosphoribosylaminoimidazole carboxylase, EC 4.1.1.21, and phosphoribosylaminoimidazolesuccinocarboxamide synthetase, EC 6.3.2.6, activities

Ovis aries

4137

copurification of the enzymes of the de novo purine biosynthetic pathway

Pigeon

1403

streptomycin precipitation, ammonium sulfate precipitation, phenyl Sepharose 6 column chromatography, hydroxyapatite column chromatography, and Superdex 200 gel filtration

Treponema denticola

Q73PV9

714253