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4.1.1.21: phosphoribosylaminoimidazole carboxylase

This is an abbreviated version!
For detailed information about phosphoribosylaminoimidazole carboxylase, go to the full flat file.

Word Map on EC 4.1.1.21

Reaction

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
=
5-amino-1-(5-phospho-D-ribosyl)imidazole
 +
CO2

Synonyms

5-Amino-1-ribosylimidazole 5-phosphate carboxylase, 5-Phosphoribosyl-5-aminoimidazole carboxylase, AdeD, AIR carboxylase, AIRC, aminoimidazole ribonucleotide carboxylase, Carboxylyase, phosphoribosylaminoimidazole, class II PurE, PAICS, phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, PurE

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.21 phosphoribosylaminoimidazole carboxylase

KI Value

KI Value on EC 4.1.1.21 - phosphoribosylaminoimidazole carboxylase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.022
4-nitro-1-(-beta-D-ribofuranosyl)pyrazole 5'-phosphate
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0
0.0013
4-nitro-1-(beta-D-ribofuranosyl)imidazole 5'-phosphate
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0
0.00000034
4-Nitro-5-aminoimidazole ribonucleotide
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0
0.0028
5-amino-1-(beta-D-ribofuranosyl)-1,2,3-triazole-4-carboxylate 5'-phosphate
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0
0.00039
5-amino-1-(beta-D-ribofuranosyl)-4-nitropyrazole 5'-phosphate
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0
0.062
5-amino-1-(beta-D-ribofuranosyl)imidazole-4-carboxaldehyde 5'-phosphate
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0
0.006
5-amino-1-(beta-D-ribofuranosyl)pyrazole-4-carboxylate 5'-phosphate
-
in 50 mM Tris-HCl, 0.5 mM EDTA, pH 8.0