4.1.1.21: phosphoribosylaminoimidazole carboxylase

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For detailed information about phosphoribosylaminoimidazole carboxylase, go to the full flat file.

Reaction

Synonyms

5-Amino-1-ribosylimidazole 5-phosphate carboxylase, 5-Phosphoribosyl-5-aminoimidazole carboxylase, AdeD, AIR carboxylase, AIRC, aminoimidazole ribonucleotide carboxylase, Carboxylyase, phosphoribosylaminoimidazole, class II PurE, PAICS, phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, PurE

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.1 Carboxy-lyases

                4.1.1.21 phosphoribosylaminoimidazole carboxylase

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Results	in table
3213	AA Sequence
1	Application
1	CAS Registry Number
8	Cloned(Commentary)
4	Crystallization (Commentary)
1	General Stability
1	IC50 Value
11	Inhibitors
2	kcat/KM [mM/s]
7	Ki Value [mM]
5	KM Value [mM]
13	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
21	Organism
6	Pathway
139	PDB ID
1	pH Stability
2	pI Value
4	Protein Variants
7	Purification (Commentary)
1	Reaction
2	Reaction Type
21	Reference
5	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
24	Substrates and Products (Substrate)
7	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Stability [°C]
4	Turnover Number [1/s]

KM Value

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KM Value on EC 4.1.1.21 - phosphoribosylaminoimidazole carboxylase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.076

1-(5-phosphoribosyl)-5-aminoimidazole

Gallus gallus

-

-

4133

0.0038 - 0.009

4-carboxy-5-aminoimidazole ribonucleotide

2 entries

0.06

5-aminoimidazole ribonucleotide

Treponema denticola

Q73PV9

50 mM Tris-HCl (pH 8.0), at 10°C

714253

13

CO2

Treponema denticola

Q73PV9

50 mM Tris-HCl (pH 8.0), at 10°C

714253

0.0038

4-carboxy-5-aminoimidazole ribonucleotide

Treponema denticola

Q73PV9

50 mM Tris-HCl (pH 8.0), at 10°C

714253

0.009

4-carboxy-5-aminoimidazole ribonucleotide

Treponema denticola

Q73PV9

50 mM Tris-HCl (pH 8.0), at 30°C

714253