4.1.1.21: phosphoribosylaminoimidazole carboxylase

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For detailed information about phosphoribosylaminoimidazole carboxylase, go to the full flat file.

Reaction

Synonyms

5-Amino-1-ribosylimidazole 5-phosphate carboxylase, 5-Phosphoribosyl-5-aminoimidazole carboxylase, AdeD, AIR carboxylase, AIRC, aminoimidazole ribonucleotide carboxylase, Carboxylyase, phosphoribosylaminoimidazole, class II PurE, PAICS, phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, PurE

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.1 Carboxy-lyases

                4.1.1.21 phosphoribosylaminoimidazole carboxylase

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Results	in table
3213	AA Sequence
1	Application
1	CAS Registry Number
8	Cloned(Commentary)
4	Crystallization (Commentary)
1	General Stability
1	IC50 Value
11	Inhibitors
2	kcat/KM [mM/s]
7	Ki Value [mM]
5	KM Value [mM]
13	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
21	Organism
6	Pathway
139	PDB ID
1	pH Stability
2	pI Value
4	Protein Variants
7	Purification (Commentary)
1	Reaction
2	Reaction Type
21	Reference
5	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
24	Substrates and Products (Substrate)
7	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Stability [°C]
4	Turnover Number [1/s]

Application

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Application on EC 4.1.1.21 - phosphoribosylaminoimidazole carboxylase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

analysis

Cricetulus griseus

M1R995

sensitive and rapid analytical method for detection of purine de novo biosynthesis intermediates based on high performance liquid chromatography with electrochemical detection. Method is applied to accumulation of 5-aminoimidazole ribotide in AdeD cells

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