3.6.1.17: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

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For detailed information about bis(5'-nucleosyl)-tetraphosphatase (asymmetrical), go to the full flat file.

Word Map on EC 3.6.1.17

3.6.1.17

nudix

lupin

5'-tetraphosphate

5',5'-p1,p4-tetraphosphate

mutt

3.1.4.1

diphosphoinositol

angustifolius

adenosine5'tetraphospho5'adenosine

Reaction

Synonyms

(asymmetrical) diadenosine 5',5''�-P1,P4-tetraphosphate hydrolase, (asymmetrical) dinucleoside tetraphosphatase, Ap4A hydrolase, Ap4A-hydrolase, AP4AASE, Apf, asym-di-GDPase, asymmetric Ap4A hydrolase, asymmetric diadenosine tetraphosphate hydrolase, asymmetrical Ap4A hydrolase, asymmetrical bis-(5'-nucleosidyl)-tetraphosphatase, asymmetrical diadenosine tetraphosphate hydrolase, AtNUDX25 protein, ATP-producing Ap4A hydrolase, bis(5'-adenosyl)-tetraphosphatase, bis(5'-guanosyl)-tetraphosphatase, bis(5'-nucleosyl)-tetraphosphatase (asymmetrical), bis(5-guanosyl)tetraphosphatase, CT771, Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, diadenosine 5',5'-P1P4 tetraphosphate hydrolase, diadenosine 5,5-P1,P4-tetraphosphate hydrolase, diadenosine P1,P4-tetraphosphatase, Diadenosine tetraphosphatase, diadenosine tetraphosphate pyrophosphohydrolase, diguanosine tetraphosphatase, diguanosinetetraphosphatase (asymmetrical), diguanosinetetraphosphate guanosylhydrolase, dinucleoside tetraphosphatase, dinucleosidetetraphosphatase (asymmetrical), DIPP1, ENPP4, More, MXAN_1509, NDX-4, nudH, Nudix hydrolase, NUDT2, PFE1035c, PrpA

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.17 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

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Results	in table
5	Activating Compound
2233	AA Sequence
1	CAS Registry Number
11	Cloned(Commentary)
5	Crystallization (Commentary)
51	Disease/ Diagnostics
6	General Information
1	IC50 Value
108	Inhibitors
16	kcat/KM [mM/s]
37	Ki Value [mM]
74	KM Value [mM]
9	Localization
52	Metals/Ions
23	Molecular Weight [Da]
42	Natural Substrates/ Products (Substrates)
52	Organism
3	Pathway
21	PDB ID
15	pH Optimum
6	pH Range
3	pH Stability
1	pI Value
28	Protein Variants
25	Purification (Commentary)
1	Reaction
3	Reaction Type
52	Reference
22	Source Tissue
21	Specific Activity [micromol/min/mg]
2	Storage Stability
124	Substrates and Products (Substrate)
3	Subunits
55	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]
50	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.6.1.17 - bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

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5',5'-diadenosine tetraphosphate + H2O

ATP + AMP

Drosophila melanogaster

Q4V6M1

687119

diadenosine 5',5'-P1,P4-tetraphosphate + H2O

ATP + AMP

2 entries

diadenosine 5',5'-P1,P4-tetraphosphate + H2O

ATP + AMP + ?

Arabidopsis thaliana

Q9C6Z2

key enzyme controlling the in vivo concentration of diadenosine 5',5'-P1,P4 tetraphosphate (Ap4A) - an important signaling molecule involved in regulation of DNA replication and repair, signaling in stress response and apoptosis

695301

diadenosine 5',5'-P1,P5-pentaphosphate + H2O

ATP + ADP

Arabidopsis thaliana

Q9C6Z2

695301

diguanosine 5',5'-P1,P4-tetraphosphate + H2O

GTP + GMP

Arabidopsis thaliana

Q9C6Z2

695301

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O

ATP + AMP

24 entries

P1,P4-bis(5'-guanosyl)tetraphosphate + H2O

GTP + GMP

11 entries

additional information

2 entries