Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine 5'-tetraphosphate | competitive; Ki in nanomolar range | Homo sapiens | |
adenosine 5'-tetraphosphate | Ki in nanomolar range | Rattus norvegicus | |
fluoride | - |
Homo sapiens | |
fluoride | - |
Rattus norvegicus | |
Zn2+ | - |
Homo sapiens | |
Zn2+ | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0007 | - |
P1,P4-bis(5'-adenosyl) tetraphosphate | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required, optimum concentration 3-10 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
18000 | - |
SDS-PAGE, immunoblot | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | Homo sapiens | - |
ATP + AMP | - |
? | |
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | Rattus norvegicus | - |
ATP + AMP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0001 | - |
crude extract | Homo sapiens |
18.5 | - |
purified enzyme | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | - |
Homo sapiens | ATP + AMP | - |
? | |
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | - |
Rattus norvegicus | ATP + AMP | - |
? |