3.6.1.12: dCTP diphosphatase

This is an abbreviated version!
For detailed information about dCTP diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.12

3.6.1.12

nudix

mutt

ap4a

diadenosine

decapping

dihydrate

triphosphorylated

dinucleoside

5',5'-p1,p4-tetraphosphate

8-oxo-dgtpase

exoribonuclease

8-oxo-2'-deoxyguanosine

5'-end-dependent

8-oxo-dgmp

drug development

medicine

Reaction

Synonyms

all-alpha dCTP pyrophosphatase 1, all-alpha NTP pyrophosphatase, all-alpha nucleoside triphosphate pyrophosphatase, dCTP pyrophosphatase, dCTP pyrophosphatase 1, dCTPase, dCTPase 1, dCTPase-dUTPase, DCTPP1, deoxy-CTPase, deoxycytidine triphosphatase, deoxycytidine-triphosphatase, NTP pyrophosphatase, NTP pyrophosphohydrolase, phosphatase, deoxycytidine, tri-, pyrophosphohydrolase, RS21-C6, XTP3-TPA, XTP3-transactivated protein A, XTP3TPA

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.12 dCTP diphosphatase

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Results	in table
2063	AA Sequence
4	Application
1	CAS Registry Number
8	Cloned(Commentary)
1	Crystallization (Commentary)
106	Disease/ Diagnostics
3	Expression
16	General Information
95	IC50 Value
175	Inhibitors
29	kcat/KM [mM/s]
5	Ki Value [mM]
32	KM Value [mM]
5	Localization
5	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
21	Organism
5	Pathway
16	PDB ID
2	pH Optimum
2	pH Range
4	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
20	Reference
13	Source Tissue
1	Specific Activity [micromol/min/mg]
50	Substrates and Products (Substrate)
4	Subunits
39	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
29	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 3.6.1.12 - dCTP diphosphatase

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dCTP nucleotidohydrolase

The mammalian enzyme also displays weak activity against dTTP and dATP, but none against dGTP. Activity is highest with analogs including 5-iodo-dCTP and 5-methyl-dCTP.