3.6.1.12: dCTP diphosphatase
This is an abbreviated version!
For detailed information about dCTP diphosphatase, go to the full flat file.
Word Map on EC 3.6.1.12
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3.6.1.12
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nudix
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mutt
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ap4a
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diadenosine
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decapping
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dihydrate
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triphosphorylated
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dinucleoside
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5',5'-p1,p4-tetraphosphate
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8-oxo-dgtpase
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exoribonuclease
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8-oxo-2'-deoxyguanosine
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5'-end-dependent
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8-oxo-dgmp
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drug development
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medicine
- 3.6.1.12
-
nudix
-
mutt
- ap4a
-
diadenosine
-
decapping
-
dihydrate
-
triphosphorylated
-
dinucleoside
-
5',5'-p1,p4-tetraphosphate
- 8-oxo-dgtpase
- exoribonuclease
- 8-oxo-2'-deoxyguanosine
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5'-end-dependent
- 8-oxo-dgmp
- drug development
- medicine
Reaction
Synonyms
all-alpha dCTP pyrophosphatase 1, all-alpha NTP pyrophosphatase, all-alpha nucleoside triphosphate pyrophosphatase, dCTP pyrophosphatase, dCTP pyrophosphatase 1, dCTPase, dCTPase 1, dCTPase-dUTPase, DCTPP1, deoxy-CTPase, deoxycytidine triphosphatase, deoxycytidine-triphosphatase, NTP pyrophosphatase, NTP pyrophosphohydrolase, phosphatase, deoxycytidine, tri-, pyrophosphohydrolase, RS21-C6, XTP3-TPA, XTP3-transactivated protein A, XTP3TPA
ECTree
3.6.1.12 dCTP diphosphataseAdvanced search results
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Natural Substrates Products on EC 3.6.1.12 - dCTP diphosphatase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
dCTP + H2O
dCMP + diphosphate
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the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
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?
dCTP + H2O
dCMP + diphosphate
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enzyme of salvage synthesis of pyrimidine deoxyribonucleotides
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?
dCTP + H2O
dCMP + diphosphate
Tequatrovirus T4
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the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
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?
additional information
?
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human all-alpha dCTP pyrophosphatase 1 (DCTPP1) is a dNTP pyrophosphatase with high affinity for dCTP and 5'-modified dCTP derivatives
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additional information
?
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human all-alpha dCTP pyrophosphatase 1 (DCTPP1) is a dNTP pyrophosphatase with high affinity for dCTP and 5'-modified dCTP derivatives
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