3.6.1.12: dCTP diphosphatase

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For detailed information about dCTP diphosphatase, go to the full flat file.

Reaction

Synonyms

all-alpha dCTP pyrophosphatase 1, all-alpha NTP pyrophosphatase, all-alpha nucleoside triphosphate pyrophosphatase, dCTP pyrophosphatase, dCTP pyrophosphatase 1, dCTPase, dCTPase 1, dCTPase-dUTPase, DCTPP1, deoxy-CTPase, deoxycytidine triphosphatase, deoxycytidine-triphosphatase, NTP pyrophosphatase, NTP pyrophosphohydrolase, phosphatase, deoxycytidine, tri-, pyrophosphohydrolase, RS21-C6, XTP3-TPA, XTP3-transactivated protein A, XTP3TPA

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.12 dCTP diphosphatase

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Results	in table
2063	AA Sequence
4	Application
1	CAS Registry Number
8	Cloned(Commentary)
1	Crystallization (Commentary)
106	Disease/ Diagnostics
3	Expression
16	General Information
95	IC50 Value
175	Inhibitors
29	kcat/KM [mM/s]
5	Ki Value [mM]
32	KM Value [mM]
5	Localization
5	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
21	Organism
5	Pathway
16	PDB ID
2	pH Optimum
2	pH Range
4	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
20	Reference
13	Source Tissue
1	Specific Activity [micromol/min/mg]
50	Substrates and Products (Substrate)
4	Subunits
39	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
29	Turnover Number [1/s]

KI Value

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KI Value on EC 3.6.1.12 - dCTP diphosphatase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.356

5-hydroxytriptonide

Homo sapiens

-

in 50 mM Tris, pH 8.0, 100 mM KCl, 5 mM MgCl2, 100 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C

719287

0.168

triptolide

Homo sapiens

-

in 50 mM Tris, pH 8.0, 100 mM KCl, 5 mM MgCl2, 100 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C

719287

0.135

triptonide

Homo sapiens

-

in 50 mM Tris, pH 8.0, 100 mM KCl, 5 mM MgCl2, 100 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C

719287

0.085

triptriolide

Homo sapiens

-

in 50 mM Tris, pH 8.0, 100 mM KCl, 5 mM MgCl2, 100 mg/ml bovine serum albumin, 1 mM dithiothreitol, at 37°C

719287

additional information

additional information

Homo sapiens

Q9H773

inhibition kinetics

755792

-