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3.6.1.12: dCTP diphosphatase

This is an abbreviated version!
For detailed information about dCTP diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.12

Reaction

dCTP
+
H2O
=
dCMP
+
diphosphate

Synonyms

all-alpha dCTP pyrophosphatase 1, all-alpha NTP pyrophosphatase, all-alpha nucleoside triphosphate pyrophosphatase, dCTP pyrophosphatase, dCTP pyrophosphatase 1, dCTPase, dCTPase 1, dCTPase-dUTPase, DCTPP1, deoxy-CTPase, deoxycytidine triphosphatase, deoxycytidine-triphosphatase, NTP pyrophosphatase, NTP pyrophosphohydrolase, phosphatase, deoxycytidine, tri-, pyrophosphohydrolase, RS21-C6, XTP3-TPA, XTP3-transactivated protein A, XTP3TPA

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.12 dCTP diphosphatase

Substrates Products

Substrates Products on EC 3.6.1.12 - dCTP diphosphatase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-chloro-dATP + H2O
2-chloro-AMP + diphosphate
show the reaction diagram
-
-
-
?
2-hydroxy-dATP + H2O
2-hydroxy-dAMP + diphosphate
show the reaction diagram
-
-
-
?
5-bromo-dCTP + H2O
5-bromo-dCMP + diphosphate
show the reaction diagram
5-chloro-dCTP + H2O
5-chloro-dCMP + diphosphate
show the reaction diagram
-
-
-
?
5-fluoro-dUTP + H2O
5-fluoro-dUMP + diphosphate
show the reaction diagram
-
-
-
?
5-formyl-dCTP + H2O
5-formyl-dCMP + diphosphate
show the reaction diagram
-
-
-
?
5-hydroxy-dCTP + H2O
5-hydroxy-dCMP + diphosphate
show the reaction diagram
-
-
-
?
5-hydroxymethyl-dCTP + H2O
5-hydroxymethyl-dCMP + diphosphate
show the reaction diagram
-
-
-
?
5-iodo-dCTP + H2O
5-iodo-dCMP + diphosphate
show the reaction diagram
5-methyl-dCTP + H2O
5-methyl-dCMP + diphosphate
show the reaction diagram
aza-dCTP + H2O
dCMP + diphosphate
show the reaction diagram
the enzyme can hydrolyse the activated form of decitabine, aza-dCTP, and might constitute a novel route in the detoxification of this DNA-methylation inhibitor
-
-
?
CTP + H2O
CMP + diphosphate
show the reaction diagram
-
-
-
?
dATP + H2O
dAMP + diphosphate
show the reaction diagram
dCDP + H2O
?
show the reaction diagram
-
-
-
-
?
dCTP + H2O
dCMP + diphosphate
show the reaction diagram
dTTP + H2O
dTMP + diphosphate
show the reaction diagram
dUTP + H2O
dUMP + diphosphate
show the reaction diagram
additional information
?
-