3.5.2.10: creatininase

This is an abbreviated version!
For detailed information about creatininase, go to the full flat file.

Word Map on EC 3.5.2.10

3.5.2.10

sarcosine

creatinase

amidinohydrolase

amperometric

jaffe

analysis

medicine

diagnostics

Reaction

Synonyms

creatinine amidohydrolase, creatinine hydrolase, CrnA

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.2 In cyclic amides

3.5.2.10 creatininase

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Results	in table
1	Activating Compound
2108	AA Sequence
5	Application
1	CAS Registry Number
6	Cloned(Commentary)
6	Crystallization (Commentary)
5	Disease/ Diagnostics
1	General Stability
19	Inhibitors
8	kcat/KM [mM/s]
13	KM Value [mM]
13	Metals/Ions
10	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
18	Organism
1	Oxidation Stability
5	Pathway
72	PDB ID
5	pH Optimum
4	pH Range
3	pH Stability
1	Posttranslational Modification
9	Protein Variants
5	Purification (Commentary)
4	Reaction
1	Reaction Type
17	Reference
1	Renatured (Commentary)
2	Source Tissue
11	Specific Activity [micromol/min/mg]
4	Storage Stability
19	Substrates and Products (Substrate)
8	Subunits
3	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Temperature Stability [°C]
8	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.5.2.10 - creatininase

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azide

Paenarthrobacter ureafaciens

complete inhibition at the ionic strength of 2 mM

Co2+

Cu2+

cyanide

Paenarthrobacter ureafaciens

complete inhibition by 1 mM, much less inhibition by both azide and cyanide

172083

EDTA

2 entries

ethoxyformic anhydride

Fe2+

formaldehyde

heavy metal ions

Hg2+

Paenarthrobacter ureafaciens

complete inhibition at the ionic strength of 0.1 mM HgCl, 20-30% activity restored at 20 mM 2-mercaptoethanol

methanol

Mg2+

N-bromosuccinimide

o-phenanthroline

PCMB

Photooxidation

additional information

Pseudomonas putida

172079