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3.5.2.10: creatininase

This is an abbreviated version!
For detailed information about creatininase, go to the full flat file.

Word Map on EC 3.5.2.10

Reaction

creatinine
+
H2O
=
Creatine

Synonyms

creatinine amidohydrolase, creatinine hydrolase, CrnA

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.10 creatininase

Metals Ions

Metals Ions on EC 3.5.2.10 - creatininase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Co2+
-
activates
Fe2+
-
activates
Mg2+
-
activates
Ni2+
-
activates
Zinc
removal of the zinc ions by dialyzing against buffers containing o-phenanthroline results in a partial decrease of 10-30% in activity and zinc content. Wild-type enzyme, purified in the presence of EDTA, shows only half the activity of the wild-type enzyme, the activity is recovered by the addition of ZnCl2 or MnCl2