3.5.2.10: creatininase
This is an abbreviated version!
For detailed information about creatininase, go to the full flat file.
Word Map on EC 3.5.2.10
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3.5.2.10
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sarcosine
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creatinase
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amidinohydrolase
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amperometric
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jaffe
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analysis
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medicine
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diagnostics
- 3.5.2.10
- sarcosine
- creatinase
-
amidinohydrolase
-
amperometric
-
jaffe
- analysis
- medicine
- diagnostics
Reaction
Synonyms
creatinine amidohydrolase, creatinine hydrolase, CrnA
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Reaction
Reaction on EC 3.5.2.10 - creatininase
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creatinine + H2O = creatine
catalytic mechanism: a first water molecule is a hydroxide ion that is bound as a bridge between the two metal ions and attacks the carbonyl carbon of the substrate. A second water molecule is bound to the carboxyl group of Glu122 and functions as a proton donor in catalysis