3.5.1.13: aryl-acylamidase

This is an abbreviated version!
For detailed information about aryl-acylamidase, go to the full flat file.

Word Map on EC 3.5.1.13

3.5.1.13

acetylcholinesterase

aaa

cholinesterases

o-nitroacetanilide

buche

acetanilid

eserine

serotonin-sensitive

propanil

3.1.1.8

neostigmine

pharmacology

acylanilide

diagnostics

Reaction

Synonyms

AAA, aryl acylamidase, aryl acylaminidase, Azl13, EC 3.5.1.13 AAA-2, EC 3.5.1.13, AAA-1, M-1 amidase, More, PamH, polyamidase, pseudocholinesterase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.13 aryl-acylamidase

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Results	in table
13	Activating Compound
531	AA Sequence
5	Application
1	CAS Registry Number
6	Cloned(Commentary)
2	Crystallization (Commentary)
3	Disease/ Diagnostics
10	General Information
1	General Stability
3	IC50 Value
206	Inhibitors
3	kcat/KM [mM/s]
15	Ki Value [mM]
51	KM Value [mM]
13	Localization
8	Metals/Ions
14	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
92	Organism
2	PDB ID
40	pH Optimum
9	pH Range
7	pH Stability
2	pI Value
1	Posttranslational Modification
13	Protein Variants
23	Purification (Commentary)
3	Reaction
3	Reaction Type
90	Reference
54	Source Tissue
50	Specific Activity [micromol/min/mg]
7	Storage Stability
205	Substrates and Products (Substrate)
14	Subunits
40	Synonyms
1	Systematic Name
33	Temperature Optimum [°C]
3	Temperature Range [°C]
25	Temperature Stability [°C]
19	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 3.5.1.13 - aryl-acylamidase

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6-methoxy-harmalan

Rattus norvegicus

enhances activity of enzyme form AAA-1 and AAA-2

208975

6-methoxy-harman

Rattus norvegicus

enhances activity of enzyme form AAA-1 and AAA-2

208975

chlorimipramine

Rattus norvegicus

stimulates enzyme form AAA-2

208975

cyproheptadine

Rattus norvegicus

stimulates enzyme form AAA-2

208975

Harmaline

Rattus norvegicus

enhances activity of enzyme form AAA-1 and AAA-2

208975

harmalol

Rattus norvegicus

enhances activity of enzyme form of AAA-2

208975

methiothepin

Rattus norvegicus

stimulates enzyme form AAA-2

208975

N-benzyl-N-dodecyl-N,N-dimethylammonium chloride

Homo sapiens

activator at high substrate concentrations

697867

PMSF

Streptomyces sp.

A0A088BHP3

slight activation at 1 mM

733190

tyramine

3 entries

additional information

Streptomyces sp.

A0A088BHP3

no effect by EDTA, 8-hydroxyquinoline, and 2-mercaptoethanol

733190