3.4.24.B28: ADAM15
This is an abbreviated version!
For detailed information about ADAM15, go to the full flat file.
Word Map on EC 3.4.24.B28
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3.4.24.B28
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metalloprotease
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ectodomains
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metalloprotease-disintegrins
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rgd-dependent
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metargidin
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medicine
- 3.4.24.B28
- metalloprotease
- ectodomains
-
metalloprotease-disintegrins
-
rgd-dependent
- metargidin
- medicine
Reaction
proteolysis of proteins =
Synonyms
a disintegrin and metalloproteinase 15, ADAM15 endopeptidase, ADAM15 isoforms i1, ADAM15 isoforms i2, ADAM15 isoforms i3, ADAM15 isoforms i4, ADAM15 isoforms i5, ADAM15 isoforms i6
ECTree
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Reference
Reference on EC 3.4.24.B28 - ADAM15
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Kleino, I.; Ortiz, R.M.; Yritys, M.; Huovila, A.P.; Saksela, K.
Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins
J. Cell. Biochem.
108
877-885
2009
Homo sapiens
Ungerer, C.; Doberstein, K.; Buerger, C.; Hardt, K.; Boehncke, W.H.; Boehm, B.; Pfeilschifter, J.; Dummer, R.; Mihic-Probst, D.; Gutwein, P.
ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma
Biochem. Biophys. Res. Commun.
401
363-369
2010
Homo sapiens
Rybnikova, E.; Gluschenko, T.; Galeeva, A.; Tulkova, E.; Nalivaeva, N.N.; Makova, N.Z.; Turner, A.J.; Samoilov, M.
Differential expression of ADAM15 and ADAM17 metalloproteases in the rat brain after severe hypobaric hypoxia and hypoxic preconditioning
Neurosci. Res.
72
364-373
2012
Rattus norvegicus
Boehm, B.B.; Freund, I.; Krause, K.; Kinne, R.W.; Burkhardt, H.
ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling
Arthritis Rheumatol.
65
2826-2834
2013
Homo sapiens (Q13444)
Hou, Y.; Chu, M.; Du, F.F.; Lei, J.Y.; Chen, Y.; Zhu, R.Y.; Gong, X.H.; Ma, X.; Jin, J.
Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells
Biochem. Biophys. Res. Commun.
435
640-645
2013
Homo sapiens (Q13444), Homo sapiens
Lee, H.D.; Kim, Y.H.; Koo, B.H.; Kim, D.S.
The ADAM15 ectodomain is shed from secretory exosomes
BMB Rep.
48
277-282
2015
Homo sapiens (Q13444)
Hou, Y.; Chu, M.; Du, F.; Dai, H.; Chen, Y.; Jin, J.
Expression and activity of human serum albumin recombinant human disintegrin domain of ADAM15 fusion protein
Chin. J. Biol.
26
1551-1555
2013
Homo sapiens (Q13444)
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Lee, H.D.; Koo, B.H.; Kim, Y.H.; Jeon, O.H.; Kim, D.S.
Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes
FASEB J.
26
3084-3095
2012
Homo sapiens (Q13444), Homo sapiens
Fried, D.; Boehm, B.B.; Krause, K.; Burkhardt, H.
ADAM15 protein amplifies focal adhesion kinase phosphorylation under genotoxic stress conditions
J. Biol. Chem.
287
21214-21223
2012
Homo sapiens (Q13444)
Duan, X.; Mao, X.; Sun, W.
ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells
Mol. Med. Rep.
7
991-997
2013
Homo sapiens (Q13444)
Pasten, K.; Bastian, Y.; Roa-Espitia, A.L.; Maldonado-Garcia, D.; Mendoza-Hernandez, G.; Ortiz-Garcia, C.I.; Mujica, A.; Hernandez-Gonzalez, E.O.
ADAM15 participates in fertilization through a physical interaction with acrogranin
Reproduction
148
623-634
2014
Cavia porcellus (H0UVJ8), Cavia porcellus
Moss, M.L.; Miller, M.A.; Vujanovic, N.; Yoneyama, T.; Rasmussen, F.H.
Fluorescent substrates for ADAM15 useful for assaying and high throughput screening
Anal. Biochem.
514
42-47
2016
Homo sapiens (Q13444)
Babendreyer, A.; Molls, L.; Simons, I.M.; Dreymueller, D.; Biller, K.; Jahr, H.; Denecke, B.; Boon, R.A.; Bette, S.; Schnakenberg, U.; Ludwig, A.
The metalloproteinase ADAM15 is upregulated by shear stress and promotes survival of endothelial cells
J. Mol. Cell. Cardiol.
134
51-61
2019
Homo sapiens (Q13444)
Dong, D.D.; Zhou, H.; Li, G.
ADAM15 targets MMP9 activity to promote lung cancer cell invasion
Oncol. Rep.
34
2451-2460
2015
Homo sapiens (Q13444), Homo sapiens
Lorenzatti Hiles, G.; Bucheit, A.; Rubin, J.R.; Hayward, A.; Cates, A.L.; Day, K.C.; El-Sawy, L.; Kunju, L.P.; Daignault, S.; Lee, C.T.; Liebert, M.; Hussain, M.; Day, M.L.
ADAM15 Is functionally associated with the metastatic progression of human bladder cancer
PLoS ONE
11
e0150138
2016
Homo sapiens
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