Disease on EC 3.4.24.B28 - ADAM15
Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Acute Lung Injury
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
adam15 deficiency
A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation.
adam15 deficiency
A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice.
adam15 deficiency
ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm.
adam15 deficiency
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
adam15 deficiency
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.
Adenocarcinoma
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Adenocarcinoma
ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells.
Aneurysm
ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm.
Aortic Aneurysm, Abdominal
ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm.
Arthritis
A disintegrin and metallproteinase 15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.
Arthritis, Rheumatoid
A Disintegrin and Metalloprotease 15 is Expressed on Rheumatoid Arthritis Synovial Tissue Endothelial Cells and may Mediate Angiogenesis.
Arthritis, Rheumatoid
ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling.
Arthritis, Rheumatoid
ADAM15 in apoptosis resistance of synovial fibroblasts: converting Fas/CD95 death signals into the activation of pro-survival pathways by calmodulin recruitment.
Atherosclerosis
A Disintegrin and Metalloproteinase 15 Contributes to Atherosclerosis by Mediating Endothelial Barrier Dysfunction via Src Family Kinase Activity.
Atherosclerosis
ADAM33 expression in atherosclerotic lesions and relationship of ADAM33 gene variation with atherosclerosis.
Atherosclerosis
Loss of protease activity of ADAM15 abolishes protective effects on plaque progression in atherosclerosis.
Breast Neoplasms
Aberrant alternative exon use and increased copy number of human metalloprotease-disintegrin ADAM15 gene in breast cancer cells.
Breast Neoplasms
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Breast Neoplasms
ADAM15 mediates upregulation of Claudin-1 expression in breast cancer cells.
Breast Neoplasms
ADAM15 participates in fertilization through a physical interaction with acrogranin.
Breast Neoplasms
ADAM22 as a prognostic and therapeutic drug target in the treatment of endocrine-resistant breast cancer.
Breast Neoplasms
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.
Breast Neoplasms
The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation.
Carcinoma
ADAM15 to ?5?1 integrin switch in colon carcinoma cells : A late event in cancer progression associated with tumor dedifferentiation and poor prognosis.
Carcinoma, Hepatocellular
ADAM15 correlates with prognosis, immune infiltration and apoptosis in hepatocellular carcinoma.
Carcinoma, Non-Small-Cell Lung
ADAM15 targets MMP9 activity to promote lung cancer cell invasion.
Cardiomyopathy, Dilated
Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy.
Cartilage Diseases
ADAM15 MODULATES OUTSIDE-IN SIGNALING IN CHONDROCYTE-MATRIX INTERACTIONS.
Chondrosarcoma
Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage.
Choroidal Neovascularization
An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
Colitis, Ulcerative
ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease.
Colorectal Neoplasms
ADAM15 to ?5?1 integrin switch in colon carcinoma cells : A late event in cancer progression associated with tumor dedifferentiation and poor prognosis.
Crohn Disease
ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease.
Hypertension
ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm.
Immune System Diseases
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Inflammatory Bowel Diseases
ADAM15 to ?5?1 integrin switch in colon carcinoma cells : A late event in cancer progression associated with tumor dedifferentiation and poor prognosis.
Inflammatory Bowel Diseases
ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease.
Liver Neoplasms
ADAM15 correlates with prognosis, immune infiltration and apoptosis in hepatocellular carcinoma.
Lung Injury
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Lymphatic Metastasis
ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells.
Melanoma
ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma.
Melanoma
Identification of binding peptides of the ADAM15 disintegrin domain using phage display.
Melanoma
NCK1-AS1 promotes the progression of melanoma by accelerating cell proliferation and migration via targeting miR-526b-5p/ADAM15 axis.
Melanoma
Screening cellular proteins involved in the anti-proliferative effect of the ADAM15 disintegrin domain in murine melanoma cells.
Neoplasm Metastasis
ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma.
Neoplasm Metastasis
ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells.
Neoplasm Metastasis
ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction.
Neoplasm Metastasis
ADAM15 suppresses cell motility by driving integrin alpha5beta1 cell surface expression via Erk inactivation.
Neoplasm Metastasis
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Neoplasm Metastasis
Critical role of ADAM15 in tumor progression: targeting multiple factors for metastasis promotion.
Neoplasm Metastasis
MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling.
Neoplasm Metastasis
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Neoplasms
A Disintegrin and Metalloprotease 15 is Expressed on Rheumatoid Arthritis Synovial Tissue Endothelial Cells and may Mediate Angiogenesis.
Neoplasms
Aberrant alternative exon use and increased copy number of human metalloprotease-disintegrin ADAM15 gene in breast cancer cells.
Neoplasms
ADAM15 correlates with prognosis, immune infiltration and apoptosis in hepatocellular carcinoma.
Neoplasms
ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.
Neoplasms
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Neoplasms
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Neoplasms
ADAM15 Is Functionally Associated with the Metastatic Progression of Human Bladder Cancer.
Neoplasms
ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells.
Neoplasms
ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction.
Neoplasms
ADAM15 to ?5?1 integrin switch in colon carcinoma cells : A late event in cancer progression associated with tumor dedifferentiation and poor prognosis.
Neoplasms
Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins.
Neoplasms
Antitumor and anti-angiogenic activity of the recombinant human disintegrin domain of A disintegrin and metalloproteinase 15.
Neoplasms
Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation.
Neoplasms
Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.
Neoplasms
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Neoplasms
Critical role of ADAM15 in tumor progression: targeting multiple factors for metastasis promotion.
Neoplasms
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
Neoplasms
Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes.
Neoplasms
Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis.
Neoplasms
Identification of binding peptides of the ADAM15 disintegrin domain using phage display.
Neoplasms
MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling.
Neoplasms
Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.
Neoplasms
Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells.
Neoplasms
The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?
Neoplasms
The microRNA miR-3174 Suppresses the Expression of ADAM15 and Inhibits the Proliferation of Patient-Derived Bladder Cancer Cells.
Neoplasms
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Nevus
ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma.
Osteoarthritis
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.
Osteoarthritis
Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage.
Ovarian Neoplasms
ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.
Pancreatic Neoplasms
ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells.
Pneumonia
A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice.
Pneumonia
ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets.
Prostatic Neoplasms
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Prostatic Neoplasms
ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction.
Prostatic Neoplasms
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Prostatic Neoplasms
EGF promotes the shedding of soluble E-cadherin in an ADAM10-dependent manner in prostate epithelial cells.
Prostatic Neoplasms
Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.
Prostatic Neoplasms
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Pulmonary Disease, Chronic Obstructive
A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice.
Pulmonary Disease, Chronic Obstructive
ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction.
Pulmonary Edema
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Retinal Neovascularization
An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
Sepsis
A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation.
Starvation
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.
Status Epilepticus
ADAM9, ADAM10, and ADAM15 mRNA levels in the rat brain after kainic acid-induced status epilepticus.
Stomach Neoplasms
Expression of ADAM9 in CIN3 lesions and squamous cell carcinomas of the cervix.
Stomach Neoplasms
The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer.
Thrombosis
ADAM 15 is an adhesion receptor for platelet GPIIb-IIIa and induces platelet activation.
Triple Negative Breast Neoplasms
Functional exosome-mediated co-delivery of doxorubicin and hydrophobically modified microRNA 159 for triple-negative breast cancer therapy.
Urinary Bladder Neoplasms
ADAM15 Is Functionally Associated with the Metastatic Progression of Human Bladder Cancer.
Urinary Bladder Neoplasms
The microRNA miR-3174 Suppresses the Expression of ADAM15 and Inhibits the Proliferation of Patient-Derived Bladder Cancer Cells.
Urogenital Neoplasms
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
Vesicular Stomatitis
TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15.
html completed