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3.4.24.75: lysostaphin

This is an abbreviated version!
For detailed information about lysostaphin, go to the full flat file.

Word Map on EC 3.4.24.75

Reaction

Hydrolysis of the -Gly-/-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans =

Synonyms

ALE-1, BSYX-L210, Glycyl-glycine endopeptidase, Glycylglycine endopeptidase, Lspn, Lss, Lst, LYS, lysostaphin, Lysostaphin endopeptidase, LytU, More, peptidoglycan endopeptidase, r-Lys, r-lysostaphin, sa0205, SH3b, Staphylococcus aureus-specific cell wall endopeptidase lysostaphin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.75 lysostaphin

pH Optimum

pH Optimum on EC 3.4.24.75 - lysostaphin

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6
-
highest specific activity (turbidity reduction assay)
8
enzyme obtained from pET vector system
additional information
-
the pH value near a negatively charged cell is supposed to be strongly shifted to acidity as compared to the pH of the solution volume. This shifts the enzyme pH dependence curve in solution to alkalinity, overview