3.4.24.75: lysostaphin

This is an abbreviated version!
For detailed information about lysostaphin, go to the full flat file.

Word Map on EC 3.4.24.75

3.4.24.75

staphylococci

methicillin-resistant

vancomycin

simulans

bactericidal

pentaglycine

bacteriolytic

methicillin

epidermidis

mastitis

antistaphylococcal

cross-bridge

bacteriocins

staphylolyticus

medicine

autolysins

oxacillin

endolysins

interpeptide

teichoic

biovar

intramammary

coagulase-negative

muropeptide

teicoplanin

methicillin-sensitive

cowan

micrococci

murein

haemolyticus

coagulase

daptomycin

mutanolysine

diagnostics

pharmacology

food industry

analysis

Reaction

Hydrolysis of the -Gly-/-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans =

Synonyms

ALE-1, BSYX-L210, Glycyl-glycine endopeptidase, Glycylglycine endopeptidase, Lspn, Lss, Lst, LYS, lysostaphin, Lysostaphin endopeptidase, LytU, More, peptidoglycan endopeptidase, r-Lys, r-lysostaphin, sa0205, SH3b, Staphylococcus aureus-specific cell wall endopeptidase lysostaphin

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.75 lysostaphin

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Results	in table
3	Activating Compound
2147	AA Sequence
26	Application
1	CAS Registry Number
38	Cloned(Commentary)
3	Crystallization (Commentary)
7	General Information
5	General Stability
40	Inhibitors
7	KM Value [mM]
16	Localization
20	Metals/Ions
26	Molecular Weight [Da]
42	Natural Substrates/ Products (Substrates)
6	Organic Solvent Stability
108	Organism
33	PDB ID
16	pH Optimum
5	pH Range
4	pH Stability
2	pI Value
3	Posttranslational Modification
26	Protein Variants
32	Purification (Commentary)
2	Reaction
1	Reaction Type
88	Reference
1	Renatured (Commentary)
16	Specific Activity [micromol/min/mg]
3	Storage Stability
92	Substrates and Products (Substrate)
15	Subunits
43	Synonyms
6	Temperature Optimum [°C]
2	Temperature Range [°C]
9	Temperature Stability [°C]

KM Value

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KM Value on EC 3.4.24.75 - lysostaphin

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0.07

L-lysine(N-e-pentaglycine-N-(2-aminobenzoyl))-[N-(2,4-dinitrophenyl)ethylenediamine]

Staphylococcus simulans

value from Grafit and Hanes plot analyses

670460

0.07 - 0.08

L-lysine(N-e-pentaglycyl-DABCYL)-EDANS

2 entries

0.2 - 0.3

N-(2-Aminobenzoyl)pentaglycine-[N-(2,4-dinitrophenyl)ethylenediamine]

2 entries

additional information

2 entries