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3.4.24.75: lysostaphin

This is an abbreviated version!
For detailed information about lysostaphin, go to the full flat file.

Word Map on EC 3.4.24.75

Reaction

Hydrolysis of the -Gly-/-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans =

Synonyms

ALE-1, BSYX-L210, Glycyl-glycine endopeptidase, Glycylglycine endopeptidase, Lspn, Lss, Lst, LYS, lysostaphin, Lysostaphin endopeptidase, LytU, More, peptidoglycan endopeptidase, r-Lys, r-lysostaphin, sa0205, SH3b, Staphylococcus aureus-specific cell wall endopeptidase lysostaphin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.75 lysostaphin

Activating Compound

Activating Compound on EC 3.4.24.75 - lysostaphin

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
C-terminus of TRAP
-
i.e. target of RNAIII activating protein, a membrane-associated protein in Staphylococcus sp., can enhance the activity of lysozyme and lysostaphin, interaction analysis, overview
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low molecular weight chitosan
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low molecular weight chitosan is able to enhance the action of lysostaphin against staphylococcal cells more efficiently than high molecular weight chitosan
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additional information
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the enzyme acts synergistically with oxacillin and with vancomycin in lysis of the cell wall of pathogenic Staphylococcus aureus
-