Any feedback?
Literature summary for 3.4.24.75 extracted from
- Ionogenic groups in the active site of lysostaphin. Kinetic and thermodynamic data compared with x-ray crystallographic data (2007), Biochemistry (Moscow), 72, 989-993.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | kinetics and thermodynamics | Staphylococcus simulans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus simulans | - |
biovar staphylolyticus, strain GNTs PM No. 1030 | - |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| Hydrolysis of the -Gly-/-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans | a two-stage reaction controlled by two ionogenic groups of the active site, the active site of lysostaphin contains glutamic acid and lysine | Staphylococcus simulans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | pentaglycine bridges in peptidoglycan of Staphylococci as a substrate | Staphylococcus simulans | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| More | lysostaphin-type enzymes belong to so-called LAS, i.e. Lysostaphin, D-Ala-D-Ala carboxypeptidase, Sonic hedgehog enzyme, enzymes | Staphylococcus simulans |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Staphylococcus simulans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
the pH value near a negatively charged cell is supposed to be strongly shifted to acidity as compared to the pH of the solution volume. This shifts the enzyme pH dependence curve in solution to alkalinity, overview | Staphylococcus simulans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4.5 | 10.3 | - |
Staphylococcus simulans |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
