3.4.23.B19: plasmepsin V

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For detailed information about plasmepsin V, go to the full flat file.

Word Map on EC 3.4.23.B19

3.4.23.B19

plasmepsins

plasmodium

malaria

falciparum

erythrocyte

pexel

antimalarial

vacuole

aspartyl

parasitophorous

vivax

translocon

pepstatin

asexual

toxoplasma

hydroxyethylamine

peptidomimetics

phosphatidylinositol-3-phosphate

cytoadherence

exportome

picomolar

intraerythrocytic

Reaction

cleavage of hemoglobin. In contrast to the food vacuole plasmepsins, detergent-solubilized PM V does not bind the aspartic protease inhibitor pepstatin. =

Synonyms

plasmepsin V, Plm V, PlmV, PM V, PMV, PMVm84, PMVp37

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.23 Aspartic endopeptidases

3.4.23.B19 plasmepsin V

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Results	in table
3	AA Sequence
6	Cloned(Commentary)
11	General Information
28	IC50 Value
77	Inhibitors
20	kcat/KM [mM/s]
20	KM Value [mM]
11	Localization
4	Natural Substrates/ Products (Substrates)
18	Organism
3	pH Optimum
2	pH Range
7	Protein Variants
6	Purification (Commentary)
1	Reaction
18	Reference
2	Renatured (Commentary)
4	Source Tissue
12	Specific Activity [micromol/min/mg]
43	Substrates and Products (Substrate)
8	Subunits
22	Synonyms
1	Temperature Optimum [°C]
20	Turnover Number [1/s]

Purification

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Purification on EC 3.4.23.B19 - plasmepsin V

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HisTrap column chromatography

Plasmodium vivax

A0A0H4FQ60

754670

HisTrap column chromatography and Hitrap Q column chromatography

2 entries

HiTrap Q column chromatography and HisTrap column chromatography

Plasmodium falciparum

Q8I6Z5

752860

Superdex 75 gel filtration

2 entries