3.4.23.B19: plasmepsin V
This is an abbreviated version!
For detailed information about plasmepsin V, go to the full flat file.
Word Map on EC 3.4.23.B19
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3.4.23.B19
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plasmepsins
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plasmodium
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malaria
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falciparum
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erythrocyte
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pexel
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antimalarial
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vacuole
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aspartyl
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parasitophorous
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vivax
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translocon
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pepstatin
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asexual
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toxoplasma
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hydroxyethylamine
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peptidomimetics
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phosphatidylinositol-3-phosphate
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cytoadherence
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exportome
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picomolar
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intraerythrocytic
- 3.4.23.B19
-
plasmepsins
- plasmodium
- malaria
- falciparum
- erythrocyte
-
pexel
-
antimalarial
- vacuole
-
aspartyl
-
parasitophorous
- vivax
-
translocon
- pepstatin
-
asexual
- toxoplasma
-
hydroxyethylamine
-
peptidomimetics
- phosphatidylinositol-3-phosphate
-
cytoadherence
-
exportome
-
picomolar
-
intraerythrocytic
Reaction
cleavage of hemoglobin. In contrast to the food vacuole plasmepsins, detergent-solubilized PM V does not bind the aspartic protease inhibitor pepstatin. =
Synonyms
plasmepsin V, Plm V, PlmV, PM V, PMV, PMVm84, PMVp37
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 3.4.23.B19 - plasmepsin V
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REACTION DIAGRAM
erythrocyte membrane protein 2 + H2O
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i.e. Dabcyl-RYVRILSETEE-Edans
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histidine-rich protein II + H2O
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i.e. Dabcyl-LNKRLLHETQE-Edans
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additional information
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PM V pull-downs identified an ER-resident HSP70 and HSP101 as associated proteins
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