3.4.22.67: zingipain
This is an abbreviated version!
For detailed information about zingipain, go to the full flat file.
Word Map on EC 3.4.22.67
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3.4.22.67
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rhizome
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zingiber
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officinale
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actinidin
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tender
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bromelain
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roscoe
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food industry
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nutrition
- 3.4.22.67
- rhizome
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zingiber
- officinale
- actinidin
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tender
- bromelain
- roscoe
- food industry
- nutrition
Reaction
preferential cleavage of peptides with a proline residue at the P2 position =
Synonyms
Bgp, C01.017, cysteine proteinase GP-II, F50, ginger protease, ginger protease II, GP-II, zingibain
ECTree
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General Information
General Information on EC 3.4.22.67 - zingipain
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evolution
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the enzyme has sequence similarity with zingipain-1 from Zingiber officinalis
physiological function
additional information
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the enzyme has cysteine protease activity, but also a significant acetylcholinesterase inhibitor activity exhibiting noncompetitive inhibition of acetylcholinesterase for the hydrolysis of acetylthiocholine iodide with a Ki value of 9.31 mg/ml., overview
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zingipain shows antiproliferative activities against fungi, i.e. Fusarium oxysporum, Exserohilum turicicum, and Collectotrichum cassicola, and human malignant cell lines, e.g. Hep-G2 and SW-620, although not against bacterial cells
physiological function
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zingipain shows antiproliferative activities against fungi, i.e. Fusarium oxysporum, Exserohilum turicicum, and Collectotrichum cassicola, and human malignant cell lines, e.g. Hep-G2 and SW-620, although not against bacterial cells
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